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IL13RA2 and PAX2
Data Source:
BioGRID
(two hybrid)
IL13RA2
PAX2
Description
interleukin 13 receptor subunit alpha 2
paired box 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Integral Component Of Membrane
Receptor Complex
Chromatin
Nucleus
Nucleoplasm
Lysosome
Microtubule Organizing Center
Protein-containing Complex
Protein-DNA Complex
Centriolar Satellite
Molecular Function
Cytokine Receptor Activity
Protein Binding
Cytokine Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Immunoglobulin Production
Immunoglobulin Mediated Immune Response
Cytokine-mediated Signaling Pathway
Negative Regulation Of Mast Cell Degranulation
Urogenital System Development
Branching Involved In Ureteric Bud Morphogenesis
Cell Fate Determination
Mesonephros Development
Neural Tube Closure
Optic Cup Morphogenesis Involved In Camera-type Eye Development
Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Retinal Pigment Epithelium Development
Regulation Of Transcription By RNA Polymerase II
Axonogenesis
Mesodermal Cell Fate Specification
Aging
Visual Perception
Glial Cell Differentiation
Optic Nerve Development
Optic Nerve Morphogenesis
Optic Nerve Structural Organization
Vestibulocochlear Nerve Formation
Response To Nutrient Levels
Regulation Of Metanephros Size
Ureter Maturation
Pronephric Field Specification
Inner Ear Morphogenesis
Camera-type Eye Development
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Kinase B Signaling
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Pronephros Development
Brain Morphogenesis
Anatomical Structure Development
Stem Cell Differentiation
Positive Regulation Of Epithelial Cell Proliferation
Mesenchymal To Epithelial Transition
Optic Chiasma Development
Cellular Response To Hydrogen Peroxide
Cellular Response To Retinoic Acid
Cellular Response To Glucose Stimulus
Cellular Response To Epidermal Growth Factor Stimulus
Metanephric Mesenchyme Development
Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis
Metanephric Mesenchymal Cell Differentiation
Nephric Duct Formation
Ureter Development
Metanephric Collecting Duct Development
Metanephric Epithelium Development
Metanephric Distal Convoluted Tubule Development
Metanephric Nephron Tubule Formation
Positive Regulation Of Metanephric Glomerulus Development
Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis
Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation
Reactive Oxygen Species Metabolic Process
Cochlea Development
Cochlea Morphogenesis
Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis
Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development
Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development
Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development
Negative Regulation Of Reactive Oxygen Species Metabolic Process
Positive Regulation Of Metanephric DCT Cell Differentiation
Positive Regulation Of Optic Nerve Formation
Pathways
Interleukin-4 and Interleukin-13 signaling
Drugs
AER001
Diseases
Renal coloboma syndrome (RCS); Papillorenal syndrome
GWAS
Adult body size (
32376654
)
Alcohol consumption (drinks per week) (
30679032
)
Alzheimer's disease (
20061627
)
Bitter alcoholic beverage consumption (
31046077
)
BMI (adjusted for smoking behaviour) (
28443625
)
Body mass index (
28892062
)
Body mass index (joint analysis main effects and smoking interaction) (
28443625
)
Body size at age 10 (
32376654
)
Cerebrospinal fluid t-tau:AB1-42 ratio (
30153862
)
Diastolic blood pressure (
27841878
)
Heart rate increase in response to exercise (
29497042
)
Heart rate response to exercise (
29769521
)
Heart rate response to recovery post exercise (
29769521
)
Heart rate response to recovery post exercise (10 sec) (
29497042
)
Heart rate response to recovery post exercise (20 sec) (
29497042
)
Heart rate response to recovery post exercise (30 sec) (
29497042
)
Heart rate response to recovery post exercise (40 sec) (
29497042
)
Heart rate response to recovery post exercise (50 sec) (
29497042
)
Refractive error (
32231278
)
Regular attendance at a pub or social club (
29970889
)
Systolic blood pressure (
28135244
27841878
30578418
)
Interacting Genes
17 interacting genes:
AKT1
BAG4
BRMS1
CASP8
EGFR
ERBB2
ESR2
IGF1R
IL13
IL4
IL4R
NOTCH2
PALB2
PAX2
PIK3CA
PLPP6
RB1CC1
24 interacting genes:
BBS1
BBS2
BBS4
BBS7
BEX1
BLID
GLCE
ID2
IL13RA2
KLK6
KLK9
MAPK8
MAPK8IP1
MRC2
NSD3
PAXIP1
PRDM14
RASL10B
RB1
SFRP2
SNAI1
TRIM25
VPS45
WT1
Entrez ID
3598
5076
HPRD ID
02132
01330
Ensembl ID
ENSG00000123496
ENSG00000075891
Uniprot IDs
Q14627
Q02962
PDB IDs
3LB6
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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