KRTAP5-3 and RAMP3

Data Source:
BioGRID (two hybrid)

		KRTAP5-3	RAMP3
Description		keratin associated protein 5-3	receptor activity modifying protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Lysosome Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Receptor Complex Amylin Receptor Complex 3 Adrenomedullin Receptor Complex
	Molecular Function	Protein Binding	Amyloid-beta Binding Adrenomedullin Receptor Activity Protein Binding Coreceptor Activity Amylin Receptor Activity
	Biological Process	Keratinization	Angiogenesis Positive Regulation Of Receptor Recycling Calcium Ion Transport Intracellular Protein Transport G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Gene Expression Positive Regulation Of Protein Kinase A Signaling Positive Regulation Of Cell Death Protein Transport Receptor Internalization Cellular Response To Hormone Stimulus Positive Regulation Of Peptidyl-serine Phosphorylation Cross-receptor Inhibition Within G Protein-coupled Receptor Heterodimer Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade Cellular Response To Estradiol Stimulus Protein Localization To Plasma Membrane G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Amylin Receptor Signaling Pathway Positive Regulation Of Protein Localization To Plasma Membrane Response To Amyloid-beta Positive Regulation Of Calcium Ion Import Across Plasma Membrane Adrenomedullin Receptor Signaling Pathway
Pathways		Keratinization	G alpha (s) signalling events Calcitonin-like ligand receptors ADORA2B mediated anti-inflammatory cytokines production
Drugs		Beta-D-Glucose	Pramlintide
Diseases
GWAS			Hepatic lipid content in extreme obesity ( 25246029)
Interacting Genes		43 interacting genes: ADAMTSL4 CATSPER1 CRCT1 CYSRT1 ECM1 FBXO34 FUCA2 GLRX3 HOXA1 KPRP KRTAP1-3 KRTAP1-5 KRTAP10-8 KRTAP11-1 KRTAP15-1 KRTAP4-2 KRTAP5-1 KRTAP5-9 KRTAP9-2 KRTAP9-3 LCE1A LCE1B LCE1C LCE1D LCE1F LCE2C LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RAMP3 RGS17 SMCP	15 interacting genes: CALCR CALCRL CYSRT1 HSPB3 KRTAP10-3 KRTAP5-3 KRTAP5-7 KRTAP5-9 KRTAP9-3 NBPF19 NOTCH2NLA NSF PDCD6IP SLC31A2 VIPR1
Entrez ID		387266	10268
HPRD ID		12395	05517
Ensembl ID		ENSG00000196224	ENSG00000122679
Uniprot IDs		Q6L8H2	A4D2L1 O60896
PDB IDs			6UUS 6UVA
Enriched GO Terms of Interacting Partners?
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