SP110 and AGAP1

  • Data Source:
  • BioGRID (affinity chromatography technology)

SP110

AGAP1

Description SP110 nuclear body protein ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Image No pdb structure No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199)
  • Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025)
  • Chronic lymphocytic leukemia ( 18758461 28165464 24292274)
  • Crohn's disease ( 28067908)
  • Inflammatory bowel disease ( 28067908)
  • Obesity-related traits ( 23251661)
  • Subcutaneous adipose tissue ( 26480920)
  • Adult body size ( 32376654)
  • Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600)
  • Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
  • Craniofacial microsomia ( 26853712)
  • Mean corpuscular hemoglobin ( 29403010)
  • Mean corpuscular volume ( 29403010)
  • Menarche (age at onset) ( 23667675)
  • Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)
Interacting Genes 11 interacting genes: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9 14 interacting genes: APP ARF1 ARF6 CDC42 GRB7 GUCY1A1 GUCY1B1 RAC1 RHOA RSPH14 SMN1 SRC TK1 ZNF534
Entrez ID 3431 116987
HPRD ID 06832 16359
Ensembl ID ENSG00000135899 ENSG00000157985
Uniprot IDs Q9HB58 B2RZG9 Q9UPQ3 X5D293
PDB IDs
Enriched GO Terms of Interacting Partners?
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