AGAP1 and RSPH14

Data Source:
BioGRID (two hybrid)

		AGAP1	RSPH14
Description		ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	radial spoke head 14 homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Cellular_component
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	Molecular_function Protein Binding
	Biological Process	Protein Transport Positive Regulation Of GTPase Activity	Biological_process
Pathways
Drugs
Diseases
GWAS		Adult body size ( 32376654) Aspartate aminotransferase levels in non-alcoholic fatty liver disease ( 31311600) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Craniofacial microsomia ( 26853712) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Menarche (age at onset) ( 23667675) Venlafaxine response in generalised anxiety disorder (responders vs non-responders after 24 weeks) ( 28437668)	Serum parathyroid hormone levels ( 27927781)
Interacting Genes		14 interacting genes: APP ARF1 ARF6 CDC42 GRB7 GUCY1A1 GUCY1B1 RAC1 RHOA RSPH14 SMN1 SRC TK1 ZNF534	41 interacting genes: ABI2 AGAP1 ALS2CL AP1M1 AP2M1 AP3M1 BPIFA1 CCDC102B CDR2 CNTROB COG6 EPS8 FHL3 GABPB1 GOLGA2 JUP KASH5 KIFC3 KRT15 KRT31 KRT40 KRT75 KRT76 LZTS1 MNS1 PIBF1 POLR1C REL RPH3AL RSPH3 SEPTIN12 SMAD4 TCF4 TRAF2 TRIM27 TRIM50 TRIM69 TRIM7 VPS9D1 ZNF474 ZNF629
Entrez ID		116987	27156
HPRD ID		16359	16136
Ensembl ID		ENSG00000157985	ENSG00000100218
Uniprot IDs		B2RZG9 Q9UPQ3 X5D293	Q9UHP6
PDB IDs
Enriched GO Terms of Interacting Partners?
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