SP110 and OSGEP

Data Source:
BioGRID (two hybrid)

		SP110	OSGEP
Description		SP110 nuclear body protein	O-sialoglycoprotein endopeptidase
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	EKC/KEOPS Complex Nucleus Nucleoplasm Cytoplasm Plasma Membrane Nuclear Speck
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Metal Ion Binding	Protein Binding Metal Ion Binding N(6)-L-threonylcarbamoyladenine Synthase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Viral Process	TRNA Threonylcarbamoyladenosine Modification
Pathways			tRNA modification in the nucleus and cytosol
Drugs
Diseases
GWAS		B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Cholangiocarcinoma in primary sclerosing cholangitis (time to event) ( 28779025) Chronic lymphocytic leukemia ( 18758461 28165464 24292274) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Subcutaneous adipose tissue ( 26480920)	Food addiction ( 27106561)
Interacting Genes		11 interacting genes: ANXA7 CDKN1A NAP1L2 NDUFV2 OSGEP RUNX3 SMN1 TK1 TSC22D1 TTR ZSCAN9	25 interacting genes: CIAPIN1 CRIP2 EMCN GP1BA HPS6 LAGE3 LENG1 MUC1 NR3C1 NVL OPTC PDE4DIP PKP4 RBM48 REX1BD SF3B3 SHC1 SP110 SPRED1 TNS1 TP53RK WDR82 WIZ ZNF579 ZNF775
Entrez ID		3431	55644
HPRD ID		06832	10133
Ensembl ID		ENSG00000135899	ENSG00000092094
Uniprot IDs		Q9HB58	Q9NPF4
PDB IDs			6GWJ
Enriched GO Terms of Interacting Partners?
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