IFI35 and CLEC4G

Data Source:
BioGRID (two hybrid)

		IFI35	CLEC4G
Description		interferon induced protein 35	C-type lectin domain family 4 member G
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Virus Receptor Activity Protein Binding Mannose Binding Polysaccharide Binding Fructose Binding Carbohydrate Derivative Binding Glycosylated Region Protein Binding
	Biological Process	Macrophage Activation Involved In Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Type I Interferon Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling	Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of T Cell Proliferation Viral Entry Into Host Cell Regulation Of Immune Response Positive Regulation Of Viral Life Cycle
Pathways		Interferon alpha/beta signaling	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778)	Blood protein levels ( 28240269) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		12 interacting genes: BATF BCAS2 CLEC4G CYTH3 EML2 FHL2 KDM1A MAPK1 NMI PLEKHO1 TRIM55 TRIM63	26 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 WBP2
Entrez ID		3430	339390
HPRD ID		02844	16721
Ensembl ID		ENSG00000068079	ENSG00000182566
Uniprot IDs		P80217	B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1
PDB IDs
Enriched GO Terms of Interacting Partners?
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