CLEC4G and IFI35

Data Source:
BioGRID (two hybrid)

		CLEC4G	IFI35
Description		C-type lectin domain family 4 member G	interferon induced protein 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane	Extracellular Space Nucleus Cytoplasm Cytosol Membrane
	Molecular Function	Virus Receptor Activity Protein Binding Mannose Binding Polysaccharide Binding Fructose Binding Carbohydrate Derivative Binding Glycosylated Region Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Negative Regulation Of T Cell Mediated Immunity Negative Regulation Of T Cell Proliferation Viral Entry Into Host Cell Regulation Of Immune Response Positive Regulation Of Viral Life Cycle	Macrophage Activation Involved In Immune Response Negative Regulation Of Cell Population Proliferation Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Type I Interferon Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Interferon alpha/beta signaling
Drugs
Diseases
GWAS		Blood protein levels ( 28240269) Post bronchodilator FEV1 ( 26634245)	Coronary artery disease ( 29212778)
Interacting Genes		26 interacting genes: APOA1 APOH ARL13B ARSA ASGR1 AZU1 CAPN1 CPLX4 CPN1 EBAG9 EIF6 FAM209A FTL GEM IFI35 LRRC4C MAP3K11 MT-CO1 NUP214 PKLR PRDX1 PTPN5 RPSA SHBG SIGLEC12 WBP2	12 interacting genes: BATF BCAS2 CLEC4G CYTH3 EML2 FHL2 KDM1A MAPK1 NMI PLEKHO1 TRIM55 TRIM63
Entrez ID		339390	3430
HPRD ID		16721	02844
Ensembl ID		ENSG00000182566	ENSG00000068079
Uniprot IDs		B7ZKQ2 Q08G24 Q6UXB4 Q6XYD1	P80217
PDB IDs
Enriched GO Terms of Interacting Partners?
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