ZNF774 and DTX2

Data Source:
BioGRID (two hybrid)

		ZNF774	DTX2
Description		zinc finger protein 774	deltex E3 ubiquitin ligase 2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Notch Signaling Pathway Protein Ubiquitination
Pathways		Generic Transcription Pathway	Activated NOTCH1 Transmits Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus
Drugs
Diseases
GWAS		Male-pattern baldness ( 28196072) Rheumatoid arthritis ( 22446963)
Interacting Genes		77 interacting genes: BACH2 BEGAIN BLK BOLA2 BOLA2B CABP2 CALCOCO2 CARD9 CATSPER1 CCDC102B CCDC130 CCDC136 CCDC6 CCHCR1 CDK18 CDKN2D CEP63 CIB3 COL8A1 CPNE7 DTX2 DVL3 EFEMP2 EMD FAM124B FSD2 GABARAPL2 GEM GFAP GLRX3 GOLGA1 GOLGA2 GTPBP3 GYS1 GZMM HOXA1 HOXB5 HSF2BP IL16 IPO8 KANK2 KIFC3 KRTAP10-6 KRTAP10-7 KRTAP10-9 KRTAP4-5 LDOC1 LONRF1 MAGOHB MID2 MLH1 MTUS2 MYO15B NDOR1 NEK6 NID2 PIBF1 PICK1 PRPF31 PSMB1 RABEP1 RAD51D RBM11 SCNM1 SH2D4A SMAD3 STK16 TRAF2 TSTD2 USP49 VWC2 ZNF165 ZNF417 ZNF48 ZNF526 ZNF572 ZNF587	131 interacting genes: ABHD11 ABHD16A ALKBH4 ANAPC11 ANTKMT ARID5A ARMC7 ARNT2 BCL2L11 BICRAL BOLA2-SMG1P6 C10orf55 C11orf1 C19orf54 C1orf94 C20orf85 C22orf39 CCDC57 CLPP COA6 COQ8A DAZAP2 DOK3 DTX1 DTX3 ECM1 ECSIT EIF4ENIF1 EIF4G1 EYA2 FAM168A FCRL4 FHL2 FHL5 FOXI1 FTO GLYCTK GOLGA2 HDC HGS HLX HOXA1 HOXB2 HOXD12 HPCA HPCAL1 HPCAL4 HSFY1 HSFY2 IKZF3 KANK2 KLC3 KLHDC7B KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP19-1 KRTAP19-6 KRTAP19-7 KRTAP26-1 KRTAP6-1 KRTAP7-1 KRTAP8-1 LASP1 LNX1 LRP2BP MBD3L1 MDC1 MED19 MSS51 MVP MXRA8 NCALD NCS1 NHLRC4 NIF3L1 NME4 NOTCH1 OIP5 PARP1 PAX5 PLEKHF2 PLEKHG4 PLSCR1 POGZ PPP1R32 PRR32 PRR34 PSMB4 QARS1 RBM11 RBPMS RFX6 RHOXF2 RIMBP3 RUNX1 RUSC1 SEC22A SEC23A SEC23B SEPSECS SLC22A18AS SOHLH1 SPAG8 SPG21 STX12 SUMO1 TBX15 TEKT5 TENT2 TMEM42 TRIB3 TRIM35 TRIM54 TRIP13 TRIP6 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBQLN4 USP54 VGLL3 VSNL1 ZNF34 ZNF503 ZNF620 ZNF641 ZNF764 ZNF774 ZNF85
Entrez ID		342132	113878
HPRD ID		17571	16841
Ensembl ID		ENSG00000196391	ENSG00000091073
Uniprot IDs		Q6NX45	Q86UW9
PDB IDs			6IR0 6Y22 6Y2X 6Y3J
Enriched GO Terms of Interacting Partners?
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