TSPAN33 and SIT1

		TSPAN33	SIT1
Description		tetraspanin 33	signaling threshold regulating transmembrane adaptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Adherens Junction Cell Surface Pore Complex Tetraspanin-enriched Microdomain	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Enzyme Binding	Protein Binding Kinase Binding SH2 Domain Binding
	Biological Process	Cellular Protein Metabolic Process Pore Complex Assembly Protein Maturation Protein Localization To Plasma Membrane	Adaptive Immune Response Signal Transduction T Cell Homeostasis Regulation Of T Cell Activation
Pathways		Amyloid fiber formation
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Ulcerative colitis ( 23128233)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Interacting Genes		27 interacting genes: CHRM2 CISD2 CLDN7 COQ9 DARS2 ERGIC3 FAM209A GAD2 GJA8 GORAB GPR152 GPX8 KCNK5 LHFPL5 LMNA MFF MGST3 MTIF3 NEMP1 PLEKHO1 RELL2 SHISA4 SIT1 SLC35C2 SPINT1 TMEM106C TMEM45B	17 interacting genes: APOL2 BMP10 CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70
Entrez ID		340348	27240
HPRD ID		14669	05394
Ensembl ID		ENSG00000158457	ENSG00000137078
Uniprot IDs		Q86UF1	Q9Y3P8
PDB IDs
Enriched GO Terms of Interacting Partners?
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