SIT1 and APOL2

Data Source:
BioGRID (two hybrid)

		SIT1	APOL2
Description		signaling threshold regulating transmembrane adaptor 1	apolipoprotein L2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Extracellular Region Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Kinase Binding SH2 Domain Binding	Signaling Receptor Binding Protein Binding High-density Lipoprotein Particle Binding Lipid Binding
	Biological Process	Adaptive Immune Response Signal Transduction T Cell Homeostasis Regulation Of T Cell Activation	Lipid Metabolic Process Lipid Transport Acute-phase Response Multicellular Organism Development Cholesterol Metabolic Process Lipoprotein Metabolic Process Maternal Process Involved In Female Pregnancy
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)	Epigenetic age acceleration in alcohol use disorder ( 31466081)
Interacting Genes		17 interacting genes: APOL2 BMP10 CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70	33 interacting genes: AIG1 APOC2 APOC4 AR BSND CISD2 CYBC1 EBAG9 EMP1 FAM209A GET1 GJB5 ITGB2 KCNA1 LMNA MARCHF3 MFF MGST3 PANX1 PSCA SFXN5 SIT1 SLC18A1 SLC26A6 STX1A STX2 TMED8 TMEM139 TMEM45B TMEM52B TMEM60 USE1 YIPF6
Entrez ID		27240	23780
HPRD ID		05394	06263
Ensembl ID		ENSG00000137078	ENSG00000128335
Uniprot IDs		Q9Y3P8	A0A024R1M8 J3KQL8 Q9BQE5
PDB IDs
Enriched GO Terms of Interacting Partners?
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