SIT1 and ITM2A

		SIT1	ITM2A
Description		signaling threshold regulating transmembrane adaptor 1	integral membrane protein 2A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome	Golgi Apparatus Plasma Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding Kinase Binding SH2 Domain Binding	Amyloid-beta Binding Protein Binding
	Biological Process	Adaptive Immune Response Signal Transduction T Cell Homeostasis Regulation Of T Cell Activation	Plasma Cell Differentiation Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)	Birth weight ( 31043758) Graves' disease ( 23612905) Height ( 18391951) Nose size ( 27182965) Thyrotoxic hypokalemic periodic paralysis and Graves disease ( 31050781)
Interacting Genes		17 interacting genes: APOL2 BMP10 CLRN2 CSK FYN GRB2 ITM2A LCK MALL PLN PTPN11 SYK TMBIM6 TMEM140 TSPAN33 UPK1B ZAP70	7 interacting genes: CLDN7 FCGR1A FNDC9 MEOX2 SIT1 TMED9 TRIM14
Entrez ID		27240	9452
HPRD ID		05394	02200
Ensembl ID		ENSG00000137078	ENSG00000078596
Uniprot IDs		Q9Y3P8	O43736
PDB IDs
Enriched GO Terms of Interacting Partners?
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