DUSP29 and RNF40

Data Source:
BioGRID (two hybrid)

		DUSP29	RNF40
Description		dual specificity phosphatase 29	ring finger protein 40
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Protein-containing Complex	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytosol Membrane Extrinsic Component Of Membrane HULC Complex Neuron Projection Axon Terminus
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Phosphatase Activity Protein Homodimerization Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	MRNA 3'-UTR Binding Ubiquitin-protein Transferase Activity Protein Binding Syntaxin-1 Binding Ubiquitin Conjugating Enzyme Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Inactivation Of MAPK Activity Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Glucose Homeostasis Muscle Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade	Ubiquitin-dependent Protein Catabolic Process Regulation Of Mitotic Cell Cycle Histone Monoubiquitination Protein Ubiquitination Histone H2B Ubiquitination Response To Peptide Hormone Negative Regulation Of MRNA Polyadenylation Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Polyubiquitination Positive Regulation Of Histone H2B Ubiquitination
Pathways			E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases
GWAS			Immunoglobulin light chain (AL) amyloidosis ( 28025584)
Interacting Genes		25 interacting genes: AATK ARPC3 ASPA C17orf75 CNTROB DDIT4L EPHA2 ERBB3 GOLGA6A IGF1R LMTK2 LNX1 NIF3L1 NOC4L PICK1 POLR2G PSMB5 PTK7 RNF40 ROR1 ROR2 SRSF11 STX11 TCF4 TEPSIN	26 interacting genes: AMOTL2 ATM CCDC146 CDC73 DISC1 DUSP29 EEF1D ITSN1 KIF11 MEOX2 MSL1 MTNR1B NCBP1 NINL RB1 RNF20 SFR1 TRIM51 UBE2A UBE2B UBE2D2 UBE2E1 UBE2I UBE2L6 ZCCHC12 ZNF451
Entrez ID		338599	9810
HPRD ID		16846	07411
Ensembl ID		ENSG00000188716	ENSG00000103549
Uniprot IDs		Q68J44	A8K6K1 O75150
PDB IDs		2Y96
Enriched GO Terms of Interacting Partners?
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