DUSP29 and ASPA

Data Source:
BioGRID (two hybrid)

		DUSP29	ASPA
Description		dual specificity phosphatase 29	aspartoacylase
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GO Annotations	Cellular Component	Nucleus Cytoplasm Protein-containing Complex	Nucleus Cytosol
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Phosphatase Activity Protein Homodimerization Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity	Aminoacylase Activity Protein Binding Hydrolase Activity, Acting On Ester Bonds Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides Aspartoacylase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Inactivation Of MAPK Activity Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Glucose Homeostasis Muscle Cell Differentiation Negative Regulation Of ERK1 And ERK2 Cascade	Aspartate Catabolic Process Cellular Amino Acid Biosynthetic Process Central Nervous System Myelination Positive Regulation Of Oligodendrocyte Differentiation
Pathways			Aspartate and asparagine metabolism
Drugs			Aspartic acid Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Canavan disease (CD)
GWAS			Myopia (pathological) ( 23049088)
Interacting Genes		25 interacting genes: AATK ARPC3 ASPA C17orf75 CNTROB DDIT4L EPHA2 ERBB3 GOLGA6A IGF1R LMTK2 LNX1 NIF3L1 NOC4L PICK1 POLR2G PSMB5 PTK7 RNF40 ROR1 ROR2 SRSF11 STX11 TCF4 TEPSIN	2 interacting genes: ACY3 DUSP29
Entrez ID		338599	443
HPRD ID		16846	02033
Ensembl ID		ENSG00000188716	ENSG00000108381
Uniprot IDs		Q68J44	P45381 Q6FH48
PDB IDs		2Y96	2I3C 2O4H 2O53 2Q51 4MRI 4MXU 4NFR 4TNU
Enriched GO Terms of Interacting Partners?
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