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IARS1 and MIR92A1
Data Source:
BioGRID
(unspecified method)
IARS1
MIR92A1
Description
isoleucyl-tRNA synthetase 1
microRNA 92a-1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
Extracellular Exosome
Extracellular Space
Cytoplasm
Extracellular Vesicle
Molecular Function
TRNA Binding
Aminoacyl-tRNA Editing Activity
Isoleucine-tRNA Ligase Activity
Protein Binding
ATP Binding
GTPase Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Osteoblast Differentiation
TRNA Aminoacylation For Protein Translation
Isoleucyl-tRNA Aminoacylation
Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Negative Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Acute Inflammatory Response
Regulation Of Heart Contraction
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Necrotic Cell Death
Negative Regulation Of Angiogenesis
Positive Regulation Of Interleukin-6 Production
Negative Regulation Of Collagen Biosynthetic Process
Negative Regulation Of Smooth Muscle Cell Apoptotic Process
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Positive Regulation Of Apoptotic Process
Positive Regulation Of JUN Kinase Activity
Negative Regulation Of JUN Kinase Activity
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Nitric Oxide Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of JNK Cascade
Negative Regulation Of Inflammatory Response
Positive Regulation Of Inflammatory Response
Cellular Response To Fatty Acid
Cellular Response To Low-density Lipoprotein Particle Stimulus
Positive Regulation Of Monocyte Chemotactic Protein-1 Production
Cellular Stress Response To Acid Chemical
Vascular Endothelial Cell Response To Fluid Shear Stress
Blood Vessel Diameter Maintenance
Negative Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Sprouting Angiogenesis
Positive Regulation Of Sprouting Angiogenesis
Positive Regulation Of Metalloendopeptidase Activity
Negative Regulation Of Endothelial Cell-matrix Adhesion Via Fibronectin
Positive Regulation Of Endothelial Cell Activation
Positive Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell
Positive Regulation Of Leukocyte Adhesion To Arterial Endothelial Cell
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Drugs
Isoleucine
Diseases
GWAS
Interacting Genes
76 interacting genes:
APP
AR
CDC42
DUX4
EPRS1
ERBB2
GARS1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
SUMO2
76 interacting genes:
ADARB1
C1QBP
CELF1
CPSF1
CPSF2
CPSF6
CRTAP
DARS1
DDX1
DDX21
DDX3X
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
FIP1L1
FUS
G3BP2
GRSF1
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LRPPRC
MATR3
MSI2
NOL6
NONO
NUDT21
P3H1
PDCD11
PRMT1
PTBP1
PTBP3
PUF60
QARS1
RARS1
RBM14
RBM4
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
STRBP
SUGP2
SYMPK
SYNCRIP
TAF15
TRA2A
TRA2B
TRIM25
U2SURP
UPF1
UTP20
WWP2
YBX1
YBX3
Entrez ID
3376
407048
HPRD ID
02832
Ensembl ID
ENSG00000196305
ENSG00000283705
Uniprot IDs
P41252
Q6P0M4
Q7L4K8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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