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IARS1 and MIR128-1
Data Source:
BioGRID
(unspecified method)
IARS1
MIR128-1
Description
isoleucyl-tRNA synthetase 1
microRNA 128-1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
Extracellular Exosome
Extracellular Space
Molecular Function
TRNA Binding
Aminoacyl-tRNA Editing Activity
Isoleucine-tRNA Ligase Activity
Protein Binding
ATP Binding
GTPase Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
Osteoblast Differentiation
TRNA Aminoacylation For Protein Translation
Isoleucyl-tRNA Aminoacylation
Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Lipoprotein Particle Clearance
Gene Silencing By MiRNA
Cholesterol Homeostasis
Lipid Homeostasis
Negative Regulation Of Cholesterol Efflux
Negative Regulation Of Lipoprotein Transport
Positive Regulation Of Neuroinflammatory Response
Positive Regulation Of Microglial Cell Activation
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Drugs
Isoleucine
Diseases
GWAS
Body mass index (
26426971
)
Interacting Genes
76 interacting genes:
APP
AR
CDC42
DUX4
EPRS1
ERBB2
GARS1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR25
MIR29A
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
SUMO2
91 interacting genes:
AIMP1
AIMP2
APOBEC3B
ATXN2
ATXN2L
C1QBP
CASC3
CELF1
CPSF6
CRTAP
DARS1
DDX1
DDX21
DDX23
DDX3X
DHX36
DHX37
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
LSM10
LSM11
MARS1
MATR3
MSI2
NOL6
NONO
NUDT16L1
NUFIP2
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PURA
PURB
QARS1
RARS1
RBFOX2
RBM10
RBM12B
RBM14
RBM17
RBM4
RTCA
RTCB
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
SYNCRIP
TAF15
TENT2
TRA2A
TRA2B
U2SURP
UPF1
USP36
UTP20
YBX1
YBX2
YBX3
ZFR
Entrez ID
3376
406915
HPRD ID
02832
Ensembl ID
ENSG00000196305
ENSG00000207654
Uniprot IDs
P41252
Q6P0M4
Q7L4K8
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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