HIVEP1 and ALDOB

Data Source:
BioGRID (two hybrid)

		HIVEP1	ALDOB
Description		HIVEP zinc finger 1	aldolase, fructose-bisphosphate B
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Cytosol Nuclear Body	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Exosome
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II BMP Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II	Fructose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Canonical Glycolysis Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Vacuolar Proton-transporting V-type ATPase Complex Assembly
Pathways			Hereditary fructose intolerance Glycolysis Gluconeogenesis Fructose catabolism
Drugs			1,6-Fructose Diphosphate (Linear Form) sn-glycerol 3-phosphate Dihydroxyacetone phosphate
Diseases			Hereditary fructose intolerance; Fructosemia
GWAS		Adult body size ( 32376654) Alcohol and nicotine co-dependence ( 22488850) Asthma ( 32296059) Body mass index ( 28892062 25673413 29273807) Chronotype ( 30696823) Feeling worry ( 29500382) Figural/spatial cognitive ability ( 31620175) General risk tolerance (MTAG) ( 30643258) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Lymphocyte percentage of white cells ( 32888494) Metabolite levels ( 23823483) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494) Takayasu arteritis ( 25604533)	Age-related cataracts ( 25352737) Liver enzyme levels (alkaline phosphatase) ( 22001757) Serum alkaline phosphatase levels ( 29403010)
Interacting Genes		70 interacting genes: ALDOB APH1A APTX ASGR1 ATXN1 ATXN1L BANP BHLHE40 BNIP3 BRCA1 CACNA1A CCNK CDC37 CLK1 CREB1 DNAJA1 ELOA EMG1 FAM104B GAA GSDMB HPD HSPA1A IGFN1 IMMT KDF1 MAGED1 MAPK14 MAPK8 MIEN1 MTMR3 NFYC NHLH1 NINJ1 NRF1 NUCB1 OGT OTX1 PLEKHB2 POGZ POU2F1 POU6F2 PRKAR1A PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RAB1A RBM47 RBPMS RIDA RNF186 ROR2 SDCBP SERTAD1 SH3KBP1 SMAD3 SNX4 SOCS3 SOX10 SP4 SRPK2 STAT3 TENT5B TMEM176A VEZF1 ZC3H10 ZFHX3	22 interacting genes: AGXT2 ALDOA APP ATP6V1E1 BMPR1A BUB1 CDKN2A CTNNA1 DCC FLCN HIVEP1 HSPA8 MAP2K4 MCC MLH1 MLH3 MUC20 NRAS SMAD4 SRC STK11 TXN2
Entrez ID		3096	229
HPRD ID		01925	01972
Ensembl ID		ENSG00000095951	ENSG00000136872
Uniprot IDs		P15822	A0A024R145 P05062
PDB IDs		1BBO 3ZNF 4ZNF	1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?
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