ALDOB and AGXT2

Data Source:
BioGRID (two hybrid)

		ALDOB	AGXT2
Description		aldolase, fructose-bisphosphate B	alanine--glyoxylate aminotransferase 2
Image			No pdb structure
GO Annotations	Cellular Component	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Exosome	Mitochondrion Mitochondrial Matrix
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding	Alanine-glyoxylate Transaminase Activity Pyridoxal Phosphate Binding (R)-3-amino-2-methylpropionate-pyruvate Transaminase Activity
	Biological Process	Fructose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Canonical Glycolysis Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Vacuolar Proton-transporting V-type ATPase Complex Assembly	Glyoxylate Catabolic Process Glycine Biosynthetic Process, By Transamination Of Glyoxylate L-alanine Catabolic Process, By Transamination Positive Regulation Of Nitric Oxide Biosynthetic Process Glyoxylate Metabolic Process
Pathways		Hereditary fructose intolerance Glycolysis Gluconeogenesis Fructose catabolism	Glyoxylate metabolism and glycine degradation Pyrimidine catabolism
Drugs		1,6-Fructose Diphosphate (Linear Form) sn-glycerol 3-phosphate Dihydroxyacetone phosphate	Pyridoxal phosphate Pyruvic acid Glycine Alanine
Diseases		Hereditary fructose intolerance; Fructosemia
GWAS		Age-related cataracts ( 25352737) Liver enzyme levels (alkaline phosphatase) ( 22001757) Serum alkaline phosphatase levels ( 29403010)	Metabolite levels ( 21931564) Serum dimethylarginine levels (asymmetric/symetric ratio) ( 24159190) Symmetrical dimethylarginine levels ( 25245031 24159190) Urinary metabolite levels in chronic kidney disease ( 31959995) Urinary metabolite modules (eigenmetabolites) in chronic kidney disease ( 31959995) Urinary metabolites ( 26352407 21572414) Urinary metabolites (H-NMR features) ( 24586186)
Interacting Genes		22 interacting genes: AGXT2 ALDOA APP ATP6V1E1 BMPR1A BUB1 CDKN2A CTNNA1 DCC FLCN HIVEP1 HSPA8 MAP2K4 MCC MLH1 MLH3 MUC20 NRAS SMAD4 SRC STK11 TXN2	2 interacting genes: ALDOB CYP2E1
Entrez ID		229	64902
HPRD ID		01972	10638
Ensembl ID		ENSG00000136872	ENSG00000113492
Uniprot IDs		A0A024R145 P05062	Q9BYV1
PDB IDs		1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?
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