ALDOB and MUC20

Data Source:
BioGRID (two hybrid)

		ALDOB	MUC20
Description		aldolase, fructose-bisphosphate B	mucin 20, cell surface associated
Image			No pdb structure
GO Annotations	Cellular Component	Microtubule Organizing Center Cytosol Centriolar Satellite Extracellular Exosome	Extracellular Region Golgi Lumen Plasma Membrane Basal Plasma Membrane Apical Plasma Membrane Microvillus Membrane
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding Identical Protein Binding ATPase Binding Fructose-1-phosphate Aldolase Activity Fructose Binding	Identical Protein Binding
	Biological Process	Fructose Metabolic Process Gluconeogenesis Glycolytic Process NADH Oxidation Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of ATPase Activity Canonical Glycolysis Fructose Catabolic Process To Hydroxyacetone Phosphate And Glyceraldehyde-3-phosphate Vacuolar Proton-transporting V-type ATPase Complex Assembly	Activation Of MAPK Activity Stimulatory C-type Lectin Receptor Signaling Pathway O-glycan Processing Hepatocyte Growth Factor Receptor Signaling Pathway
Pathways		Hereditary fructose intolerance Glycolysis Gluconeogenesis Fructose catabolism	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC) Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS) Defective GALNT12 causes colorectal cancer 1 (CRCS1) Dectin-2 family MET activates RAS signaling O-linked glycosylation of mucins Termination of O-glycan biosynthesis
Drugs		1,6-Fructose Diphosphate (Linear Form) sn-glycerol 3-phosphate Dihydroxyacetone phosphate
Diseases		Hereditary fructose intolerance; Fructosemia
GWAS		Age-related cataracts ( 25352737) Liver enzyme levels (alkaline phosphatase) ( 22001757) Serum alkaline phosphatase levels ( 29403010)	Estimated glomerular filtration rate ( 31015462) Lung disease severity in cystic fibrosis ( 26417704)
Interacting Genes		22 interacting genes: AGXT2 ALDOA APP ATP6V1E1 BMPR1A BUB1 CDKN2A CTNNA1 DCC FLCN HIVEP1 HSPA8 MAP2K4 MCC MLH1 MLH3 MUC20 NRAS SMAD4 SRC STK11 TXN2	3 interacting genes: ALDOB ELOVL3 MET
Entrez ID		229	200958
HPRD ID		01972	17615
Ensembl ID		ENSG00000136872	ENSG00000176945
Uniprot IDs		A0A024R145 P05062	A0A0G2JN31 A0A0G2JR26 A0A0G2JSE2 Q8N307
PDB IDs		1QO5 1XDL 1XDM
Enriched GO Terms of Interacting Partners?
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