CDR2L and RASAL3

Data Source:
BioGRID (two hybrid)

		CDR2L	RASAL3
Description		cerebellar degeneration related protein 2 like	RAS protein activator like 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Cell Cortex Membrane Extracellular Exosome Cytoplasmic Side Of Membrane
	Molecular Function	Protein Binding Identical Protein Binding	GTPase Activator Activity Protein Binding Identical Protein Binding
	Biological Process		MAPK Cascade Positive Regulation Of GTPase Activity Negative Regulation Of Ras Protein Signal Transduction Positive Regulation Of NK T Cell Proliferation
Pathways			Regulation of RAS by GAPs
Drugs
Diseases
GWAS		Alzheimer's disease in APOE e4- carriers ( 25778476) Bipolar disorder ( 31043756)	Blood protein levels ( 29875488) Lymphocyte counts ( 32888494) Monocyte count ( 32888494)
Interacting Genes		61 interacting genes: ANKRD11 BFSP2 C1orf216 C4orf46 C9orf24 CCDC146 CCDC153 CCDC185 CCDC187 CCHCR1 CDR2 COX5B EHHADH ELOA FAIM FAM161A FAM161B FAM86C1P HDAC4 HSF2BP INO80B KRT31 KRTAP13-4 LENG1 MESD OIP5 PPP1R18 PRPF31 PSME3 RASAL3 RASD1 REL RINT1 SCNM1 SH2D4A SPRY1 STX11 TBRG4 TCEANC TCHP TCP10L TFIP11 TSGA10IP UBE2I WASHC1 ZBTB42 ZNF19 ZNF250 ZNF35 ZNF417 ZNF572 ZNF629 ZNF648 ZNF655 ZNF669 ZNF688 ZNF80 ZNF835 ZSCAN22 ZSCAN23 ZSCAN26	23 interacting genes: AMOTL2 BEGAIN CCDC102B CCDC136 CDR2L DEF6 HNRNPK HOMER1 KHDRBS3 KRT27 MTUS2 NTAQ1 PICK1 PPP1R13B PRKAA2 RABGEF1 RASD1 SNRPA TP53BP2 WASF3 YWHAE YWHAZ ZRANB1
Entrez ID		30850	64926
HPRD ID		11041	10977
Ensembl ID		ENSG00000109089	ENSG00000105122
Uniprot IDs		A0A024R8R6 Q86X02	Q86YV0
PDB IDs
Enriched GO Terms of Interacting Partners?
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