Description |
complement factor H |
zinc finger and BTB domain containing 16 |
Image |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
- Advanced age-related macular degeneration ( 26691988)
- Age-related macular degeneration ( 20385819 20385826 22694956 23326517 23577725 23455636 23536807 20861866 21665990 15761122)
- Age-related macular degeneration (choroidal neovascularisation) ( 22705344)
- Age-related macular degeneration (extreme sampling) ( 23577725)
- Age-related macular degeneration (geographic atrophy) ( 22705344)
- Age-related macular degeneration (MTAG) ( 32277175)
- Blood protein levels ( 29875488 28240269)
- Chronic central serous retinopathy ( 30480742 30073298)
- Circulating myeloperoxidase levels (serum) ( 23620142)
- Complement C3 and C4 levels ( 23028341)
- Complement factor H binding to malondialdehyde ( 32321835)
- Disease progression in age-related macular degeneration ( 29346644)
- Disease progression to choroidal neovascularization form in age-related macular degeneration ( 29346644)
- Disease progression to geographic atrophy form in age-related macular degeneration ( 29346644)
- Early age-related macular degeneration ( 32843070)
- Exudative age-related macular degeneration ( 25629512)
- Fuchs's corneal dystrophy ( 28358029)
- Matrix metalloproteinase-8 levels ( 29212897)
- Meningococcal disease ( 20694013)
- Neovascular age-related macular degeneration ( 28703135)
- Nephropathy ( 21399633)
- Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
- Serum C3d:C3 ratio (systemic complement activation) ( 29398083)
- Sub-foveal choroidal thickness ( 29844195)
- Systemic lupus erythematosus ( 28714469)
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Interacting Genes |
16 interacting genes:
ADM
C3
CFHR1
CFI
CRP
DMP1
EP300
GRB2
ITGAM
PTX3
SELL
SMAD3
THBS1
VDR
YTHDC1
ZBTB16
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154 interacting genes:
ACP5
ADAMTS4
AGTR2
AMOTL2
ANAPC5
ANXA7
AR
ATP6AP2
ATP7B
BCL6
BLZF1
BMI1
CARD9
CASP3
CCDC130
CCDC85B
CCHCR1
CD81
CDK1
CDK4
CDKN1A
CEBPA
CEP70
CEP72
CFH
CIDEA
COG6
COQ6
CTDSP1
DLST
DNAAF5
DNM2
DPM1
EEF1A1
EFHC2
EIF2S2
ENOX1
EP300
EPN1
ERVK-6
ESR1
FAM217B
FAM90A1
FCHO1
FHL2
FHL5
FSHR
GATA1
GATA2
GCSH
GNE
GOLGA2
GOLGA6L9
GPANK1
GRB7
GSTM4
HBEGF
HDAC1
HDAC2
HDAC3
HDAC4
HDAC5
HDAC6
HDAC7
HDAC9
HDX
HOXA1
HOXC5
HSF2BP
ICAM3
IL6
KIAA1549
KIFC3
KRT40
KRTAP4-12
LAMTOR5
LDOC1
LMTK3
LRIG1
LSM2
LYAR
MAGEA11
MAP3K3
MCUB
MEOX2
MID2
MTUS2
MX1
MYLIP
NCOR1
NCOR2
NFKBID
NME4
NR3C1
OSBPL3
PAFAH1B3
PARP1
PGAM5
PHF1
PIAS2
PIBF1
PLSCR1
PMAIP1
PML
PNRC2
PRKAR1B
PSMD11
PSMD2
QTRT1
RAB27A
RAB3IP
RARA
RB1
REL
RFLNB
RINT1
RUNX1T1
RXRA
SH2D4A
SIN3A
SIN3B
SMAD3
SMN1
SP1
SPOP
SPRY2
SUMO1
TAB2
TERF1
THNSL2
TK1
TLE5
TOLLIP
TRAF1
TRAF2
TRAF4
TRIM21
TRIM23
TRIM27
TRIM54
TTC23
TXNIP
UBE2I
VDR
VTA1
WASHC1
WDR33
ZBTB32
ZBTB42
ZNF24
ZNF281
ZNF552
ZNF620
ZNF655
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Entrez ID |
3075 |
7704 |
HPRD ID |
00601 |
11762 |
Ensembl ID |
ENSG00000000971
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ENSG00000109906
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Uniprot IDs |
A0A024R962
A0A0D9SG88
P08603
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A0A024R3C6
Q05516
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PDB IDs |
1FHC
1HAQ
1HCC
1HFH
1HFI
1KOV
2BZM
2G7I
2IC4
2JGW
2JGX
2KMS
2QFG
2QFH
2RLP
2RLQ
2UWN
2V8E
2W80
2W81
2WII
2XQW
3GAU
3GAV
3GAW
3KXV
3KZJ
3OXU
3R62
3RJ3
3SW0
4AYD
4AYE
4AYI
4AYM
4B2R
4B2S
4J38
4K12
4ONT
4ZH1
5NBQ
5O32
5O35
5WTB
6ATG
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1BUO
1CS3
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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