RHOD and ANKFY1

Data Source:
BioGRID (two hybrid)

		RHOD	ANKFY1
Description		ras homolog family member D	ankyrin repeat and FYVE domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Early Endosome Cytosol Cytoskeleton Plasma Membrane Cell Cortex Endosome Membrane Cytoplasmic Vesicle Cell Projection Intracellular Membrane-bounded Organelle	Lysosomal Membrane Endosome Early Endosome Cytosol Endosome Membrane Membrane Retromer Complex Intracellular Membrane-bounded Organelle Macropinosome Extracellular Exosome
	Molecular Function	GTPase Activity GTP Binding Protein Kinase Binding	Protein Binding Small GTPase Binding Metal Ion Binding Phosphatidylinositol Phosphate Binding
	Biological Process	Actin Filament Organization Establishment Or Maintenance Of Cell Polarity Rho Protein Signal Transduction Regulation Of Cell Shape Cell Migration Lamellipodium Assembly Positive Regulation Of Cell Migration Cortical Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Positive Regulation Of Cell Adhesion Focal Adhesion Assembly Actin Filament Bundle Assembly Regulation Of Small GTPase Mediated Signal Transduction	Endocytosis Endosomal Transport Endosomal Vesicle Fusion Retrograde Transport, Endosome To Golgi Positive Regulation Of Pinocytosis Golgi To Lysosome Transport
Pathways		Rho GTPase cycle RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Height ( 20881960 25282103)	Diastolic blood pressure ( 30578418) Functional impairment in major depressive disorder, bipolar disorder and schizophrenia ( 24039173) Hematocrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		13 interacting genes: ACVR1 ADCK5 ADRB2 ANKFY1 BMPR1B DIAPH2 HRAS IHH PLXNA1 SMAD2 SMAD4 SMURF2 TGFBR1	7 interacting genes: ANKRD28 CLK1 EHD1 RAB5A RHOD RHOF SRPK2
Entrez ID		29984	51479
HPRD ID		05776	09717
Ensembl ID		ENSG00000173156	ENSG00000185722
Uniprot IDs		E9PIG5 O00212	B3KPZ0 Q9P2R3
PDB IDs		2J1L
Enriched GO Terms of Interacting Partners?
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