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DNMT3L and HAND1
Data Source:
BioGRID
(pull down)
DNMT3L
HAND1
Description
DNA methyltransferase 3 like
heart and neural crest derivatives expressed 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytosol
ESC/E(Z) Complex
Chromatin
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
RNA Polymerase II Transcription Regulator Complex
Molecular Function
Protein Binding
Enzyme Activator Activity
Enzyme Binding
Metal Ion Binding
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Transcription Coregulator Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Transcription Factor Binding
Enzyme Binding
Identical Protein Binding
Protein Homodimerization Activity
BHLH Transcription Factor Binding
Biological Process
DNA Methylation
Regulation Of Gene Expression By Genetic Imprinting
Male Meiosis I
Spermatogenesis
DNA Methylation On Cytosine
DNA Methylation Involved In Gamete Generation
Negative Regulation Of Transcription, DNA-templated
Stem Cell Differentiation
Regulation Of Catalytic Activity
Negative Regulation Of DNA Methylation
Positive Regulation Of DNA Methylation
Negative Regulation Of Transcription By RNA Polymerase II
Angiogenesis
Mesoderm Formation
Blastocyst Development
Trophectodermal Cell Differentiation
Heart Looping
Embryonic Heart Tube Formation
Cardiac Left Ventricle Formation
Cardiac Right Ventricle Formation
Regulation Of Transcription By RNA Polymerase II
Heart Development
Developmental Process
Embryonic Heart Tube Development
Odontogenesis Of Dentin-containing Tooth
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Septum Morphogenesis
Mesenchyme Development
Cartilage Morphogenesis
Trophoblast Giant Cell Differentiation
Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways
DNA methylation
Drugs
Diseases
GWAS
Chin dimples (
27182965
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Electrocardiographic traits (
32602732
)
Global electrical heterogeneity phenotypes (
29622589
)
Monobrow (
27182965
)
QRS complex (Cornell) (
27659466
)
QRS duration (
30679814
27577874
31251759
25035420
)
Interacting Genes
78 interacting genes:
-
ASH2L
ATF1
ATF2
ATF3
ATF4
BLZF1
CDX2
CREB1
CREBL2
CREM
DDIT3
DLX4
DMTF1
DNMT3A
DNMT3B
DR1
E2F3
E2F5
E2F6
EGR1
EGR2
EGR4
ESR1
ESR2
ETS1
F2RL1
FOS
FOSB
FOSL1
FOSL2
GATA1
GMEB1
GSK3B
GTF2H2
GTF2I
GTF3C5
H2AC20
H2BC21
H3C14
H4C14
HAND1
HAND2
HDAC1
HNF4G
HOXA5
HOXC11
ID1
JUN
JUNB
KLF12
LDB1
LHX2
MAFK
MECP2
MED7
MEF2A
MEF2D
NFIL3
NFKB1
NR1H2
NR1I2
NR1I3
NR2E1
NR3C1
NR6A1
NUDT21
PDZD4
PHPT1
RELA
RSL24D1
RXRA
SMAD1
SMAD3
SMAD4
TLE5
TP53
YY1
15 interacting genes:
ACHE
DNMT3L
FHL2
HAND2
HEY2
HEYL
KRTAP10-6
MEF2A
MYOD1
PPP2R5D
PRKACA
PRKCA
SRA1
TCF12
TCF3
Entrez ID
29947
9421
HPRD ID
09417
03871
Ensembl ID
ENSG00000142182
ENSG00000113196
Uniprot IDs
Q9UJW3
O96004
PDB IDs
2PV0
2PVC
2QRV
4U7P
4U7T
5YX2
6BRR
6F57
6KDA
6KDB
6KDL
6KDP
6KDT
6U8P
6U8V
6U8W
6U8X
6U90
6U91
6W89
6W8B
6W8D
6W8J
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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