HAND1

Description		heart and neural crest derivatives expressed 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm RNA Polymerase II Transcription Regulator Complex
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Coregulator Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Transcription Factor Binding Enzyme Binding Identical Protein Binding Protein Homodimerization Activity BHLH Transcription Factor Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Mesoderm Formation Blastocyst Development Trophectodermal Cell Differentiation Heart Looping Embryonic Heart Tube Formation Cardiac Left Ventricle Formation Cardiac Right Ventricle Formation Regulation Of Transcription By RNA Polymerase II Heart Development Developmental Process Embryonic Heart Tube Development Odontogenesis Of Dentin-containing Tooth Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Septum Morphogenesis Mesenchyme Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways
Drugs
Diseases
GWAS		Chin dimples ( 27182965) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 32602732) Global electrical heterogeneity phenotypes ( 29622589) Monobrow ( 27182965) QRS complex (Cornell) ( 27659466) QRS duration ( 30679814 27577874 31251759 25035420)
Novel Interacting Genes		1 novel interacting genes: G3BP1
Interacting Genes		15 interacting genes: ACHE DNMT3L FHL2 HAND2 HEY2 HEYL KRTAP10-6 MEF2A MYOD1 PPP2R5D PRKACA PRKCA SRA1 TCF12 TCF3
Entrez ID		9421
HPRD ID		03871
Ensembl ID		ENSG00000113196
Uniprot IDs		O96004
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?