PYCR2 and CIC

		PYCR2	CIC
Description		pyrroline-5-carboxylate reductase 2	capicua transcriptional repressor
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Pyrroline-5-carboxylate Reductase Activity Protein Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Proline Biosynthetic Process Cellular Amino Acid Biosynthetic Process Cellular Response To Oxidative Stress L-proline Biosynthetic Process	Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated
Pathways		Glutamate and glutamine metabolism
Drugs		NADH Proline
Diseases
GWAS			Bitter alcoholic beverage consumption ( 31046077) Neutrophil count ( 32888494)
Interacting Genes		3 interacting genes: APP CIC SKIL	13 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GOLGA2 GTPBP3 NFYC PICK1 POLR1H PYCR2 SEC62 SETD2 TRIM22
Entrez ID		29920	23152
HPRD ID		17939	10831
Ensembl ID		ENSG00000143811	ENSG00000079432
Uniprot IDs		A0A087WTV6 A0A0S2Z5U6 Q96C36	A0A0A0MQR4 Q96RK0
PDB IDs		6LHM	2M41 4J2J 4J2L 6JRP 6KZG 6KZH
Enriched GO Terms of Interacting Partners?
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