CIC and POLR1H

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CIC	POLR1H
Description		capicua transcriptional repressor	RNA polymerase I subunit H
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Intracellular Membrane-bounded Organelle	Nucleoplasm RNA Polymerase I Complex
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding	Nucleic Acid Binding DNA-directed 5'-3' RNA Polymerase Activity Protein Binding Zinc Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Brain Development Learning Memory Social Behavior Negative Regulation Of Transcription, DNA-templated	Nucleobase-containing Compound Metabolic Process Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription MRNA Cleavage Positive Regulation Of Gene Expression, Epigenetic
Pathways			NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination
Drugs
Diseases
GWAS		Bitter alcoholic beverage consumption ( 31046077) Neutrophil count ( 32888494)
Interacting Genes		13 interacting genes: ATXN1 CENPJ CSNK2B GABPB1 GOLGA2 GTPBP3 NFYC PICK1 POLR1H PYCR2 SEC62 SETD2 TRIM22	18 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 TRIML2 UBE2I ZNF593
Entrez ID		23152	30834
HPRD ID		10831	09601
Ensembl ID		ENSG00000079432	ENSG00000066379
Uniprot IDs		A0A0A0MQR4 Q96RK0	Q2L6J2 Q9P1U0
PDB IDs		2M41 4J2J 4J2L 6JRP 6KZG 6KZH
Enriched GO Terms of Interacting Partners?
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