GTF3C1 and ASCC2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		GTF3C1	ASCC2
Description		general transcription factor IIIC subunit 1	activating signal cointegrator 1 complex subunit 2
Image		No pdb structure
GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm Nucleolus Membrane Ribonucleoprotein Complex	Nucleus Nucleoplasm Nuclear Speck Activating Signal Cointegrator 1 Complex
	Molecular Function	DNA Binding Protein Binding	Protein Binding Ubiquitin Binding
	Biological Process	Transcription By RNA Polymerase III Transcription Initiation From RNA Polymerase III Promoter RRNA Transcription TRNA Transcription 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III	DNA Dealkylation Involved In DNA Repair Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter	ALKBH3 mediated reversal of alkylation damage
Drugs
Diseases
GWAS		Asthma ( 31959851) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Red blood cell count ( 32888494)	Bipolar disorder or attention deficit hyperactivity disorder ( 27890468) Crohn's disease ( 28067908) Hemoglobin levels ( 32327693) IgA levels ( 28628107) Immature fraction of reticulocytes ( 27863252) Inflammatory bowel disease ( 28067908) Mean corpuscular hemoglobin concentration ( 32888494) Refractive error ( 32231278) Telomere length ( 24478790) Tonsillectomy ( 27941131) Type 2 diabetes ( 30297969) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		23 interacting genes: AGTRAP AKTIP ASCC2 CHN1 CMTM5 CPE CSNK1E DEDD EZH2 FGFR3 GTF3C4 HGH1 IGFBP3 KLF6 MAGEA4 MAPK10 PRPF38A RBM23 SNU13 SUMO2 SUPT5H TBC1D17 UBE3A	41 interacting genes: ASS1 CKAP4 CUTC DEAF1 EEF1D ELAC2 FAF1 FBP1 FUNDC2 GADD45A GFER GNL3 GTF3C1 IGSF9 IMMT KATNAL1 KDM1A LPL MAP3K1 MED31 MYH9 OLA1 PCBD2 PIK3CD PIN4 PJA1 POLA2 POLDIP2 PRPF18 RADIL RNF11 RPA1 RPLP1 SASH1 SMURF1 SNRPB SNW1 TBC1D17 TRIP4 UBC URM1
Entrez ID		2975	84164
HPRD ID		07540	16515
Ensembl ID		ENSG00000077235	ENSG00000100325
Uniprot IDs		Q12789	A0A024R1E1 A0A024R1F9 Q9H1I8
PDB IDs			2DI0 6YXQ
Enriched GO Terms of Interacting Partners?
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