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GTF2F2 and ATF2
Data Source:
HPRD
(in vitro)
GTF2F2
ATF2
Description
general transcription factor IIF subunit 2
activating transcription factor 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Transcription Factor TFIIF Complex
Microtubule Cytoskeleton
Transcription Preinitiation Complex
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Outer Membrane
Site Of Double-strand Break
H4 Histone Acetyltransferase Complex
Molecular Function
DNA Binding
DNA Helicase Activity
Protein Binding
ATP Binding
RNA Polymerase II General Transcription Initiation Factor Activity
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Activating Transcription Factor Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Chromatin Binding
DNA-binding Transcription Factor Activity
Histone Acetyltransferase Activity
Protein Binding
CAMP Response Element Binding Protein Binding
H4 Histone Acetyltransferase Activity
Protein Kinase Binding
CAMP Response Element Binding
H2B Histone Acetyltransferase Activity
Protein-containing Complex Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
MRNA Splicing, Via Spliceosome
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
DNA Duplex Unwinding
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Negative Regulation Of Transcription By RNA Polymerase II
Outflow Tract Morphogenesis
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Response To Osmotic Stress
Cellular Response To DNA Damage Stimulus
Response To Water Deprivation
Positive Regulation Of Gene Expression
Negative Regulation Of Angiogenesis
Intra-S DNA Damage Checkpoint
Positive Regulation Of Transforming Growth Factor Beta2 Production
Positive Regulation Of Neuron Apoptotic Process
Histone H4 Acetylation
Histone H2B Acetylation
Fat Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Epithelial Cell Proliferation
Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of DNA-binding Transcription Factor Activity
Adipose Tissue Development
Amelogenesis
Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Transcriptional activation of mitochondrial biogenesis
HATs acetylate histones
Circadian Clock
Activation of the AP-1 family of transcription factors
TP53 Regulates Transcription of DNA Repair Genes
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Estrogen-dependent gene expression
NGF-stimulated transcription
NGF-stimulated transcription
Response of EIF2AK4 (GCN2) to amino acid deficiency
Response of EIF2AK4 (GCN2) to amino acid deficiency
Drugs
Pseudoephedrine
Diseases
GWAS
Normal facial asymmetry (angle of surface orientation score) (
30631343
)
Type 2 diabetes (
25760438
)
Intake of total sugars (
31005972
)
Metabolite levels (
23823483
)
Interacting Genes
30 interacting genes:
AHR
AR
ARNT
ATF2
ATF4
CEBPG
CREB1
DYNLT2B
FHL2
FOS
GTF2B
GTF2E1
GTF2E2
GTF2F1
HMGA1
HTATSF1
JUN
KLF5
MAPRE3
MSX2
MYC
POLR2E
RPL27A
TAF5
TBP
TCEA1
TRAM2
URI1
YEATS4
ZMYND19
63 interacting genes:
APP
AR
ATF3
ATF4
ATF7
BACH1
BANP
BATF
CCDC6
CCND1
CEBPA
CEBPB
CEBPG
CENPQ
CREB5
CSNK2A1
CSNK2A2
DDIT3
DNMT3L
EDF1
ETS1
EXOSC8
FOS
FOSB
FOSL1
FOSL2
GTF2F2
H2BC21
HMGA1
IRF2BP1
JDP2
JUN
KIFC3
LHX8
MACROH2A1
MAPK1
MAPK10
MAPK11
MAPK13
MAPK14
MAPK8
MAPK9
MAPKAPK5
MLH1
NBN
NCOA6
PIAS2
PML
PRKCE
RB1
RNF4
RPS6KA5
RUVBL2
SMAD3
SMAD4
SPOPL
SRA1
SUMO1
THRB
UBE2I
UTF1
XPO1
YY1
Entrez ID
2963
1386
HPRD ID
01804
00443
Ensembl ID
ENSG00000188342
ENSG00000115966
Uniprot IDs
A0A024RDU9
P13984
A4D7V5
P15336
PDB IDs
1BBY
1F3U
2BBY
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6O9L
1BHI
1T2K
4H36
Enriched GO Terms of Interacting Partners
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