PHPT1 and DNMT3L

Data Source:
HPRD (two hybrid)

		PHPT1	DNMT3L
Description		phosphohistidine phosphatase 1	DNA methyltransferase 3 like
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Nuclear Body Extracellular Exosome	Nucleus Cytosol ESC/E(Z) Complex
	Molecular Function	Protein Binding Calcium Channel Inhibitor Activity Ion Channel Binding Protein Histidine Phosphatase Activity	Protein Binding Enzyme Activator Activity Enzyme Binding Metal Ion Binding
	Biological Process	Protein Dephosphorylation Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Peptidyl-histidine Dephosphorylation Negative Regulation Of T Cell Receptor Signaling Pathway Negative Regulation Of Lyase Activity Positive Regulation Of Cell Motility Regulation Of Actin Cytoskeleton Reorganization Negative Regulation Of ATP Citrate Synthase Activity	DNA Methylation Regulation Of Gene Expression By Genetic Imprinting Male Meiosis I Spermatogenesis DNA Methylation On Cytosine DNA Methylation Involved In Gamete Generation Negative Regulation Of Transcription, DNA-templated Stem Cell Differentiation Regulation Of Catalytic Activity Negative Regulation Of DNA Methylation Positive Regulation Of DNA Methylation
Pathways			DNA methylation
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: ATXN1 ATXN1L CDC42 DNMT3L ERBB3 PPP1R16A TINF2 UBC	78 interacting genes: - ASH2L ATF1 ATF2 ATF3 ATF4 BLZF1 CDX2 CREB1 CREBL2 CREM DDIT3 DLX4 DMTF1 DNMT3A DNMT3B DR1 E2F3 E2F5 E2F6 EGR1 EGR2 EGR4 ESR1 ESR2 ETS1 F2RL1 FOS FOSB FOSL1 FOSL2 GATA1 GMEB1 GSK3B GTF2H2 GTF2I GTF3C5 H2AC20 H2BC21 H3C14 H4C14 HAND1 HAND2 HDAC1 HNF4G HOXA5 HOXC11 ID1 JUN JUNB KLF12 LDB1 LHX2 MAFK MECP2 MED7 MEF2A MEF2D NFIL3 NFKB1 NR1H2 NR1I2 NR1I3 NR2E1 NR3C1 NR6A1 NUDT21 PDZD4 PHPT1 RELA RSL24D1 RXRA SMAD1 SMAD3 SMAD4 TLE5 TP53 YY1
Entrez ID		29085	29947
HPRD ID		17849	09417
Ensembl ID		ENSG00000054148	ENSG00000142182
Uniprot IDs		Q9NRX4 V9HWC4	Q9UJW3
PDB IDs		2AI6 2HW4 2NMM 2OZW 2OZX	2PV0 2PVC 2QRV 4U7P 4U7T 5YX2 6BRR 6F57 6KDA 6KDB 6KDL 6KDP 6KDT 6U8P 6U8V 6U8W 6U8X 6U90 6U91 6W89 6W8B 6W8D 6W8J
Enriched GO Terms of Interacting Partners?
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