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TRIM42 and TRAF1
Data Source:
BioGRID
(two hybrid)
TRIM42
TRAF1
Description
tripartite motif containing 42
TNF receptor associated factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Cytosol
Cytoplasmic Side Of Plasma Membrane
Plasma Membrane Signaling Receptor Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Tumor Necrosis Factor Receptor Binding
Protein Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Binding
Thioesterase Binding
Identical Protein Binding
Biological Process
Apoptotic Process
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Tumor Necrosis Factor-mediated Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of JNK Cascade
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein-containing Complex Assembly
Protein K63-linked Ubiquitination
Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways
Regulation of TNFR1 signaling
TNFR1-induced NFkappaB signaling pathway
Drugs
Diseases
GWAS
Bipolar disorder (body mass index interaction) (
24322204
)
Refractive astigmatism (
25367360
)
Allergic disease (asthma, hay fever or eczema) (
29083406
)
Asthma (
32296059
)
Celiac disease or Rheumatoid arthritis (
21383967
)
Eosinophil percentage of white cells (
32888494
)
Lymphocyte counts (
32888494
27863252
)
Lymphocyte percentage of white cells (
32888494
)
Monocyte count (
32888494
)
Pulse pressure (
30578418
)
Refractive error (
32231278
)
Rheumatoid arthritis (
30891314
24782177
23143596
24390342
20453842
19503088
)
Rheumatoid arthritis (ACPA-positive) (
23143596
24532676
)
White blood cell count (
32888494
)
Interacting Genes
145 interacting genes:
ADAMTSL4
AQP1
ARMC7
ARNT2
ARRDC3
ATG9A
AXIN1
BACH2
BEX2
C1orf109
CARD9
CATSPER1
CBY2
CCDC120
CCDC24
CCDC33
CDCA7L
CEP70
CERK
CHCHD2
CHRD
CREB5
CYSRT1
EFEMP2
EFHC2
EMD
FAM124B
FAM90A1
FBLN1
FCHO1
FNDC3B
GLI1
GLRX3
GLYCTK
GNE
GOLGA2
GUCD1
HOXA1
HOXC8
HSD3B7
IGFN1
IHO1
IKZF3
IL16
IQUB
KCTD9
KLHL38
KPRP
KRT13
KRT15
KRT34
KRT40
KRTAP10-1
KRTAP10-3
KRTAP10-5
KRTAP10-7
KRTAP10-8
KRTAP10-9
KRTAP12-2
KRTAP2-3
KRTAP2-4
KRTAP26-1
KRTAP3-2
KRTAP4-2
KRTAP4-4
KRTAP4-5
KRTAP5-11
KRTAP5-7
KRTAP9-3
L3MBTL2
LCE1A
LCE1B
LCE1C
LCE1D
LCE1E
LCE1F
LCE2A
LCE2B
LCE2C
LCE2D
LCE3A
LCE3C
LCE3D
LCE3E
LCE4A
LCE5A
LNX1
LONRF1
LZTS2
MAGOHB
MAPKBP1
MEIS2
MEOX2
MFAP1
MGAT5B
MID2
MTUS2
MVP
NBPF19
NEK8
NOTCH2NLA
OTX1
PCSK5
PHLDA1
PLSCR1
PLSCR4
PNMA1
POU4F2
PRKAB2
PROP1
PSMA1
PSMD9
PTGER3
R3HDM2
RAMAC
RCOR3
RUNX1T1
SCNM1
SHFL
SLIT1
SMARCC1
SMCP
SPAG8
SSX2IP
STK16
TASOR2
TCAF1
TFAP2D
TLX3
TMEM150A
TRAF1
TRAF2
TRAPPC2B
TRIM23
TRIM27
TXNDC5
VGLL3
VPS37A
VWC2L
YIPF3
YWHAQ
YY1
ZBTB1
ZNF330
ZNF414
245 interacting genes:
A1CF
ABHD17A
ACTN3
AKAP17A
AQP1
ARID5A
ARNT2
ARSJ
BARD1
BCAS2
BCL6
BEX2
BEX3
BIRC2
BIRC3
C1orf109
C1orf216
C2CD6
C4orf45
CARHSP1
CASP10
CASP3
CASP6
CASP8
CCDC116
CCDC120
CCDC146
CCDC185
CCDC187
CCDC198
CCHCR1
CD40
CDCA3
CDK18
CDKN1A
CDKN2B
CFLAR
CHCHD3
COX5B
CRACR2A
CRY2
CRYGA
CYB5R2
DEPTOR
DGCR6
DMRT3
DOK3
DUSP13
DUSP21
DUSP4
EBF2
EDAR
EHHADH
ENKD1
EWSR1
FAM161A
FAM161B
FAM86C1P
FBF1
FBXL18
FOSL2
GADD45GIP1
GATA1
GATA2
GATAD2B
GCA
GCM2
GEM
GFI1B
GIT2
GLIS3
GLRX3
GMCL2
GNG5
GOLGA2
GORASP2
GRAP2
HAUS1
HELT
HEY2
HGS
HIVEP3
HMG20B
HNRNPM
HOXA1
HOXB5
HOXC8
HOXD12
IKBKB
JOSD1
KANK2
KIAA1217
KIF1A
KLHL38
KPNA2
KRT3
KRT75
LATS1
LCOR
LIN37
LMNTD2
LNX1
LNX2
LRRN1
LTBR
MACIR
MAP3K14
MAP6
MAPRE2
MATR3
METTL17
MORN3
MOS
MSGN1
MYEF2
MYOZ1
NEBL
NOL4L-DT
NTAQ1
NUFIP2
NUP58
OLIG3
PATZ1
PBX3
PDE4D
PHF21A
PIN1
PITX1
PITX2
PKN1
PLAC8
PLEKHN1
POM121L4P
POP5
PPP1R13B
PPP1R32
PRDM7
PRKAB2
PSMA1
PSMB1
QRICH1
RASAL2
RASSF5
RBCK1
RBM41
RBM45
RCOR3
RIIAD1
RIPK1
RIPK2
RIPOR3
RIPPLY1
RNF31
RTP5
SAMD11
SCNM1
SDCBP2
SH3GLB2
SHARPIN
SHC3
SHFL
SIK3
SLC25A48
SLC25A6
SNRNP25
SNW1
SOHLH1
SPATA46
SPG21
SPOP
SRC
SSC5D
STK3
SUMO2
SYCE1
TANK
TBC1D16
TBC1D8
TBX18
TCEA2
TCF7L2
TCL1A
TEAD4
TFAP2D
TFAP4
TFPT
THAP7
TICAM1
TIFA
TLE5
TNFAIP3
TNFRSF11A
TNFRSF12A
TNFRSF14
TNFRSF17
TNFRSF18
TNFRSF19
TNFRSF1A
TNFRSF1B
TNFRSF4
TNFRSF8
TNFRSF9
TNFSF9
TRADD
TRAF2
TRAF3IP2
TRAF6
TRAIP
TRIM23
TRIM37
TRIM42
TRPV6
TSHZ2
TSSC4
USP2
USP7
UTP14C
VEZF1
WAC
ZBTB1
ZBTB16
ZC2HC1C
ZFYVE21
ZFYVE26
ZIC1
ZNF124
ZNF20
ZNF23
ZNF250
ZNF417
ZNF440
ZNF490
ZNF502
ZNF512B
ZNF564
ZNF572
ZNF581
ZNF587
ZNF627
ZNF648
ZNF662
ZNF669
ZNF688
ZNF697
ZNF844
Entrez ID
287015
7185
HPRD ID
15559
03418
Ensembl ID
ENSG00000155890
ENSG00000056558
Uniprot IDs
Q8IWZ5
Q13077
PDB IDs
3M0D
5E1T
5H10
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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