RTP5 and FGF14

Data Source:
BioGRID (two hybrid)

		RTP5	FGF14
Description		receptor transporter protein 5 (putative)	fibroblast growth factor 14
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Extracellular Region Nucleus Cytoplasm
	Molecular Function	Protein Binding Olfactory Receptor Binding	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity
	Biological Process	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity
Pathways		Olfactory Signaling Pathway	Phase 0 - rapid depolarisation
Drugs
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS			Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		51 interacting genes: ACTN2 ACTN3 AKAP8L APOC1 ASPG BEND5 BPIFA1 CALCOCO2 CARD9 CBY2 CIDEB COG6 DOCK8 EIF3F FGF14 GOLGA2 GOLGA6L9 HNRNPK HSF2BP KIFAP3 KRT27 KRT31 KRT33B KRT34 KRT40 KRT86 KRTAP19-5 KRTAP6-2 LZTS2 MDFI MIPOL1 MIS18A MKRN3 MTUS2 NFKBID PDE4DIP PNMA1 PNMA2 PSMA3 PSMA6 PSTPIP1 RBPMS RINT1 ROPN1 SERTAD3 SP100 SPDL1 TRAF1 TRIM23 TSGA10 USHBP1	13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA
Entrez ID		285093	2259
HPRD ID		08159	03305
Ensembl ID		ENSG00000188011	ENSG00000102466
Uniprot IDs		Q14D33	Q92915
PDB IDs
Enriched GO Terms of Interacting Partners?
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