FGF14 and H4C7

Data Source:
BioGRID (two hybrid)

		FGF14	H4C7
Description		fibroblast growth factor 14	H4 clustered histone 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm	Nucleosome Nucleus
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity	Molecular_function DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity	Nucleosome Assembly Biological_process
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)
Interacting Genes		13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA	8 interacting genes: AGTRAP APOC1 CIDEB FGF14 FKBP7 MAIP1 RHBDD2 TMED8
Entrez ID		2259	8369
HPRD ID		03305	11806
Ensembl ID		ENSG00000102466	ENSG00000275663
Uniprot IDs		Q92915	Q99525
PDB IDs
Enriched GO Terms of Interacting Partners?
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