FGF14 and HOXD12

Data Source:
BioGRID (two hybrid)

		FGF14	HOXD12
Description		fibroblast growth factor 14	homeobox D12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Cytoplasm	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Signal Transduction Cell-cell Signaling Nervous System Development Regulation Of Synaptic Plasticity Regulation Of Postsynaptic Membrane Potential Positive Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Synaptic Vesicle Recycling Regulation Of Voltage-gated Sodium Channel Activity	Skeletal System Development Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Embryonic Digit Morphogenesis
Pathways		Phase 0 - rapid depolarisation
Drugs
Diseases		Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3)
GWAS		Bone mineral density (hip) ( 30172743) Idiopathic downbeat nystagmus ( 32157568) LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931) Maximum habitual alcohol consumption ( 31151762) Plasma parathyroid hormone levels ( 30134803) PR interval ( 32439900) Preeclampsia ( 23551011) Response to methylphenidate treatment in attention-deficit/hyperactivity disorder (blood pressure) ( 21130132) Response to protease inhibitor treatment in hepatitis c (bilirubin toxicity) ( 24503447) Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes ( 28736931)	Digit length ratio ( 29659830) Digit length ratio (left hand) ( 29659830) Digit length ratio (right hand) ( 29659830) Male-pattern baldness ( 28196072)
Interacting Genes		13 interacting genes: ACACA EHHADH FBXO34 FKBP8 FUNDC2 H4C7 HOXD12 MAOB RTP5 SCN8A SMC1A SYT16 TTPA	17 interacting genes: ACTN3 CABP2 CREBBP DTX2 FGF14 FRS3 MAF MAFB MAFF MAFG MAFK MEIS1 MKRN3 POLR1C TFAP2D TRAF1 TTC19
Entrez ID		2259	3238
HPRD ID		03305	00871
Ensembl ID		ENSG00000102466	ENSG00000170178
Uniprot IDs		Q92915	P35452
PDB IDs
Enriched GO Terms of Interacting Partners?
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