TPRA1 and GPR25

Data Source:
BioGRID (two hybrid)

		TPRA1	GPR25
Description		transmembrane protein adipocyte associated 1	G protein-coupled receptor 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Lipid Metabolic Process G Protein-coupled Receptor Signaling Pathway Aging Embryonic Cleavage Negative Regulation Of Mitotic Cell Cycle Phase Transition	G Protein-coupled Receptor Signaling Pathway
Pathways			G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production
Drugs
Diseases
GWAS		Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Number of sexual partners ( 30643258) Refractive error ( 32231278) Risk-taking tendency (4-domain principal component model) ( 30643258) Triglyceride levels ( 32203549)	Ankylosing spondylitis ( 23749187) Autoimmune thyroid disease ( 32581359) Refractive error ( 32231278)
Interacting Genes		2 interacting genes: APP GPR25	32 interacting genes: AQP6 ATP6V0C ATP6V0E1 BEST2 CNIH4 CREB3L1 CREB3L3 FATE1 GGT7 GJB1 IKBIP KASH5 LDLRAD1 LMNA MAP3K7 MFSD5 MMGT1 NAALADL2 PNMA1 RETN RHCG SHISAL1 SLC16A7 SLC35E3 SLCO4A1 STOM TMEM237 TMEM248 TMEM52B TPRA1 TSPAN12 VAPB
Entrez ID		131601	2848
HPRD ID		16318	03707
Ensembl ID		ENSG00000163870	ENSG00000170128
Uniprot IDs		Q86W33	O00155
PDB IDs
Enriched GO Terms of Interacting Partners?
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