SYPL2 and GET3

Data Source:
BioGRID (two hybrid)

		SYPL2	GET3
Description		synaptophysin like 2	guided entry of tail-anchored proteins factor 3, ATPase
Image		No pdb structure
GO Annotations	Cellular Component	Integral Component Of Membrane Synaptic Vesicle Membrane	Nucleoplasm Nucleolus Cytoplasm Endoplasmic Reticulum Membrane GET Complex Extracellular Exosome
	Molecular Function	Syntaxin-1 Binding	Protein Binding ATP Binding Arsenite Transmembrane Transporter Activity ATPase Activity Metal Ion Binding
	Biological Process	Cellular Calcium Ion Homeostasis Heart Development Substantia Nigra Development T-tubule Organization	Posttranslational Protein Targeting To Endoplasmic Reticulum Membrane Arsenite Transport IRE1-mediated Unfolded Protein Response Tail-anchored Membrane Protein Insertion Into ER Membrane
Pathways			Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs			ATP
Diseases
GWAS		Body mass index ( 29273807) Chronic kidney disease ( 20383146) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Estimated glomerular filtration rate ( 31152163 31015462) Glomerular filtration rate (creatinine) ( 28452372 26831199) Major depressive disorder ( 20125088)
Interacting Genes		6 interacting genes: ATP13A1 GET3 PLLP SLC38A7 SLC41A1 YIPF2	41 interacting genes: AGR2 APLN ASPH CACNA1A CAMLG CREB3L4 EMSY FAM209A FKBP7 GET4 GOLM1 GPX7 GPX8 HILPDA IGFBP6 KCNE4 KCNE5 LDLRAD4 PDIA6 PEX14 PFDN1 PGRMC1 PGRMC2 PRB3 PRR4 RHEX SEC61A1 SEC61B SMIM19 SPP1 STATH STX5 SYPL2 TK1 TMEM154 TMEM51 TMX1 TTR VAMP2 VWC2 WFDC3
Entrez ID		284612	439
HPRD ID		17478	03555
Ensembl ID		ENSG00000143028	ENSG00000198356
Uniprot IDs		B4DYR7 Q5VXT5	O43681
PDB IDs			6SO5
Enriched GO Terms of Interacting Partners?
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