FAM98B and MIR34A

Data Source:
BioGRID (unspecified method)

		FAM98B	MIR34A
Description		family with sequence similarity 98 member B	microRNA 34a
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Intracellular Membrane-bounded Organelle TRNA-splicing Ligase Complex	Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Binding Protein Binding Protein Methyltransferase Activity Identical Protein Binding	MRNA 3'-UTR Binding MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Protein Methylation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Gene Expression	Cellular Response To DNA Damage Stimulus Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Lipid Storage Positive Regulation Of Cell Death Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration Tumor Necrosis Factor-mediated Signaling Pathway Gene Silencing By MiRNA Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Cholesterol Homeostasis Response To Axon Injury Negative Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of Smooth Muscle Cell Differentiation Negative Regulation Of Protein Kinase B Signaling Negative Regulation Of Vascular Wound Healing Triglyceride Homeostasis Positive Regulation Of Cell Cycle Arrest Cellular Response To Hypoxia Negative Regulation Of Smooth Muscle Cell Chemotaxis Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Calcium Ion Import Positive Regulation Of Blood Vessel Endothelial Cell Differentiation Negative Regulation Of Lipid Transporter Activity Negative Regulation Of Amyloid-beta Clearance Positive Regulation Of Protein Acetylation Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Positive Regulation Of Connective Tissue Replacement Positive Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Vascular Endothelial Cell Proliferation Positive Regulation Of Cellular Senescence
Pathways		tRNA processing in the nucleus
Drugs
Diseases
GWAS		Psychosis (atypical) ( 24132900) Systemic lupus erythematosus ( 24871463)	Height ( 31562340) Lean body mass ( 28552196)
Interacting Genes		20 interacting genes: MIR106A MIR10B MIR138-1 MIR141 MIR16-1 MIR18B MIR199A2 MIR200B MIR200C MIR205 MIR222 MIR34A MIR7-3 MIR9-1 MIRLET7A1 MIRLET7A2 MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G	102 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CDC5L CELF1 CPSF1 CPSF6 DARS1 DDX1 DDX21 DDX3X DDX3Y DHX36 DHX37 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FAM98B FIP1L1 FUS G3BP2 HARS2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI2 MYEF2 NOL6 NONO NUDT16L1 NUDT21 NUFIP2 PDCD11 PGAM5 PLOD1 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA QARS1 RARS1 RBFOX2 RBM12B RBM14 RBM4 RTCB SART3 SF1 SF3A1 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYMPK SYNCRIP TAF15 TIAL1 TRA2A TRA2B TRIM25 TRMT1L U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		283742	407040
HPRD ID		08786
Ensembl ID		ENSG00000171262	ENSG00000284357
Uniprot IDs		Q52LJ0
PDB IDs
Enriched GO Terms of Interacting Partners?
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