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MIR34A and SF3A3
Data Source:
BioGRID
(unspecified method)
MIR34A
SF3A3
Description
microRNA 34a
splicing factor 3a subunit 3
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Extracellular Vesicle
Nucleus
Nucleoplasm
Spliceosomal Complex
U2 SnRNP
Nuclear Speck
U2-type Precatalytic Spliceosome
Catalytic Step 2 Spliceosome
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
RNA Binding
Protein Binding
Zinc Ion Binding
Biological Process
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Tumor Necrosis Factor-mediated Signaling Pathway
Gene Silencing By MiRNA
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Cholesterol Homeostasis
Response To Axon Injury
Negative Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Differentiation
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Vascular Wound Healing
Triglyceride Homeostasis
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Hypoxia
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Blood Vessel Endothelial Cell Differentiation
Negative Regulation Of Lipid Transporter Activity
Negative Regulation Of Amyloid-beta Clearance
Positive Regulation Of Protein Acetylation
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Connective Tissue Replacement
Positive Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Vascular Endothelial Cell Proliferation
Positive Regulation Of Cellular Senescence
RNA Splicing, Via Transesterification Reactions
MRNA 3'-splice Site Recognition
MRNA Splicing, Via Spliceosome
MRNA Processing
U2-type Prespliceosome Assembly
Pathways
mRNA Splicing - Major Pathway
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Height (
31562340
)
Lean body mass (
28552196
)
Coronary artery disease (
29212778
33020668
)
Heel bone mineral density (
30598549
28869591
)
Height (
28552196
)
Pulse pressure (
28135244
)
Systolic blood pressure (
30578418
)
Interacting Genes
102 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCB
SART3
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYMPK
SYNCRIP
TAF15
TIAL1
TRA2A
TRA2B
TRIM25
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
38 interacting genes:
ADAP1
APBB1
APP
CCDC85B
HSPB1
MIR106B
MIR107
MIR141
MIR145
MIR155
MIR199A1
MIR200A
MIR200C
MIR206
MIR214
MIR221
MIR34A
MIR34B
MIR429
MIR451A
MIR7-1
MIRLET7A2
MIRLET7E
MIRLET7G
MIRLET7I
MTNR1B
PRMT5
PRPF40A
SF3A1
SREK1
TADA2A
TCERG1
TRIM69
U2AF1
VAV2
WBP4
ZDHHC17
ZNF212
Entrez ID
407040
10946
HPRD ID
10411
Ensembl ID
ENSG00000284357
ENSG00000183431
Uniprot IDs
B4DW90
Q12874
PDB IDs
2DT7
5Z56
5Z57
5Z58
6AH0
6AHD
6FF7
6QX9
6Y50
6Y53
6Y5Q
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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