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MIR34A and PLOD1
Data Source:
BioGRID
(unspecified method)
MIR34A
PLOD1
Description
microRNA 34a
procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Extracellular Vesicle
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Rough Endoplasmic Reticulum Membrane
Extracellular Exosome
Catalytic Complex
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Iron Ion Binding
Protein Binding
Procollagen-lysine 5-dioxygenase Activity
L-ascorbic Acid Binding
Procollagen Glucosyltransferase Activity
Biological Process
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Tumor Necrosis Factor-mediated Signaling Pathway
Gene Silencing By MiRNA
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Cholesterol Homeostasis
Response To Axon Injury
Negative Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Differentiation
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Vascular Wound Healing
Triglyceride Homeostasis
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Hypoxia
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Blood Vessel Endothelial Cell Differentiation
Negative Regulation Of Lipid Transporter Activity
Negative Regulation Of Amyloid-beta Clearance
Positive Regulation Of Protein Acetylation
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Connective Tissue Replacement
Positive Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Vascular Endothelial Cell Proliferation
Positive Regulation Of Cellular Senescence
Response To Hypoxia
Protein O-linked Glycosylation
Epidermis Development
Peptidyl-lysine Hydroxylation
Protein Phosphopantetheinylation
Pathways
Collagen biosynthesis and modifying enzymes
Drugs
Ascorbic acid
Diseases
Ehlers-Danlos syndrome (EDS), including: EDS classical type (EDS1/2); EDS hypermobility type (EDS3); EDS vascular type (EDS4); EDS kyphoscoliosis type (EDS6); EDS arthrochalasia type (EDS7A/7B); EDS dermatospraxis type (EDS7C); EDS autosomal recessive cardiac valvular form (EDSCV); EDS musculocontractural type (EDSMC); EDS progeroid form (EDSP); Tenascin-X deficiency (TNXD); Brittle cornea syndrome (EDS6B); EDS-like spondylocheiro dysplasia (SCD-EDS)
Nevo syndrome
GWAS
Height (
31562340
)
Lean body mass (
28552196
)
Diastolic blood pressure x alcohol consumption interaction (2df test) (
29912962
)
Moyamoya disease (
29273593
)
Platelet count (
27863252
)
Plateletcrit (
27863252
)
Tuberculosis (
29036319
)
Interacting Genes
102 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCB
SART3
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYMPK
SYNCRIP
TAF15
TIAL1
TRA2A
TRA2B
TRIM25
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
40 interacting genes:
MIR1-2
MIR10B
MIR122
MIR128-2
MIR141
MIR143
MIR15A
MIR15B
MIR17
MIR18A
MIR18B
MIR199A2
MIR19A
MIR19B1
MIR206
MIR20A
MIR214
MIR221
MIR222
MIR29B1
MIR34A
MIR34B
MIR363
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
USP4
Entrez ID
407040
5351
HPRD ID
01086
Ensembl ID
ENSG00000284357
ENSG00000083444
Uniprot IDs
Q02809
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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