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MIR34A and DDX3X
Data Source:
BioGRID
(unspecified method)
MIR34A
DDX3X
Description
microRNA 34a
DEAD-box helicase 3 X-linked
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Exosome
Extracellular Vesicle
Extracellular Region
Nucleus
Nucleoplasm
Cytoplasm
Centrosome
Cytosol
Eukaryotic Translation Initiation Factor 3 Complex
Plasma Membrane
Cytoplasmic Stress Granule
Cytosolic Small Ribosomal Subunit
Lamellipodium
Cell Leading Edge
Secretory Granule Lumen
P Granule
Extracellular Exosome
NLRP3 Inflammasome Complex
Ficolin-1-rich Granule Lumen
Molecular Function
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
DNA Binding
DNA Helicase Activity
RNA Binding
RNA Helicase Activity
MRNA Binding
GTPase Activity
Protein Binding
ATP Binding
Transcription Factor Binding
Poly(A) Binding
Eukaryotic Initiation Factor 4E Binding
ATPase Activity
Nucleoside-triphosphatase Activity
Translation Initiation Factor Binding
RNA Strand Annealing Activity
RNA Stem-loop Binding
Gamma-tubulin Binding
Ribosomal Small Subunit Binding
CTPase Activity
Protein Serine/threonine Kinase Activator Activity
Cadherin Binding
MRNA 5'-UTR Binding
Biological Process
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
Positive Regulation Of Lipid Storage
Positive Regulation Of Cell Death
Negative Regulation Of Angiogenesis
Negative Regulation Of Cell Migration
Tumor Necrosis Factor-mediated Signaling Pathway
Gene Silencing By MiRNA
Negative Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway
Cholesterol Homeostasis
Response To Axon Injury
Negative Regulation Of B Cell Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Differentiation
Negative Regulation Of Protein Kinase B Signaling
Negative Regulation Of Vascular Wound Healing
Triglyceride Homeostasis
Positive Regulation Of Cell Cycle Arrest
Cellular Response To Hypoxia
Negative Regulation Of Smooth Muscle Cell Chemotaxis
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Calcium Ion Import
Positive Regulation Of Blood Vessel Endothelial Cell Differentiation
Negative Regulation Of Lipid Transporter Activity
Negative Regulation Of Amyloid-beta Clearance
Positive Regulation Of Protein Acetylation
Negative Regulation Of Intracellular Signal Transduction
Negative Regulation Of Sprouting Angiogenesis
Negative Regulation Of Vascular Endothelial Growth Factor Production
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Connective Tissue Replacement
Positive Regulation Of Hydrogen Peroxide-induced Cell Death
Negative Regulation Of Vascular Endothelial Cell Proliferation
Positive Regulation Of Cellular Senescence
Translational Initiation
Chromosome Segregation
Gamete Generation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Response To Virus
RNA Secondary Structure Unwinding
Positive Regulation Of Gene Expression
Viral Process
Wnt Signaling Pathway
Negative Regulation Of Translation
Cell Differentiation
Positive Regulation Of Cell Growth
Negative Regulation Of Cell Growth
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Protein Autophosphorylation
DNA Duplex Unwinding
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
Stress Granule Assembly
Positive Regulation Of Toll-like Receptor 7 Signaling Pathway
Positive Regulation Of Toll-like Receptor 8 Signaling Pathway
Intracellular Signal Transduction
Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress
Mature Ribosome Assembly
Positive Regulation Of Apoptotic Process
Negative Regulation Of Apoptotic Process
Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Neutrophil Degranulation
Positive Regulation Of Viral Genome Replication
Innate Immune Response
Positive Regulation Of Translation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Translational Initiation
Lipid Homeostasis
Cellular Response To Arsenic-containing Substance
Cellular Response To Osmotic Stress
Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Canonical Wnt Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Cellular Response To Virus
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of NLRP3 Inflammasome Complex Assembly
Negative Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of NIK/NF-kappaB Signaling
Positive Regulation Of Protein Acetylation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Positive Regulation Of Protein K63-linked Ubiquitination
Protein Localization To Cytoplasmic Stress Granule
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Neutrophil degranulation
Drugs
Diseases
GWAS
Height (
31562340
)
Lean body mass (
28552196
)
Refractive error (
32231278
)
Interacting Genes
102 interacting genes:
ADARB1
AIMP1
AIMP2
APOBEC3B
AQR
ATXN2L
C1QBP
CDC5L
CELF1
CPSF1
CPSF6
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
DHX37
EDC4
EIF2AK2
EPRS1
ESRP1
FAM98A
FAM98B
FIP1L1
FUS
G3BP2
HARS2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
MYEF2
NOL6
NONO
NUDT16L1
NUDT21
NUFIP2
PDCD11
PGAM5
PLOD1
PRMT1
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM12B
RBM14
RBM4
RTCB
SART3
SF1
SF3A1
SF3A3
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SYMPK
SYNCRIP
TAF15
TIAL1
TRA2A
TRA2B
TRIM25
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX2
YBX3
ZNF346
92 interacting genes:
APBB1
CSNK2A1
DUX4
ESR1
HNF4A
IKBKE
IL7R
LINC01554
MAVS
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
NEDD4
NFKB2
NUP62
PIN1
SREK1
SRPK2
SUMO2
WBP4
XPO1
YWHAQ
ZNF512B
Entrez ID
407040
1654
HPRD ID
02154
Ensembl ID
ENSG00000284357
ENSG00000215301
Uniprot IDs
A0A2R8Y7T2
A0A2R8YFS5
O00571
PDB IDs
2I4I
2JGN
3JRV
4O2C
4O2E
4O2F
4PX9
4PXA
5E7I
5E7J
5E7M
6CZ5
6O5F
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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