SIGLEC8 and TFF1

		SIGLEC8	TFF1
Description		sialic acid binding Ig like lectin 8	trefoil factor 1
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GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Extracellular Region Extracellular Space
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Carbohydrate Binding Sialic Acid Binding	Protein Binding Growth Factor Activity
	Biological Process	Cell Adhesion Signal Transduction	Carbohydrate Metabolic Process Signal Transduction Negative Regulation Of Cell Population Proliferation Response To Iron Ion Cell Differentiation Maintenance Of Gastrointestinal Epithelium Response To Immobilization Stress Response To Peptide Hormone
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	Estrogen-dependent gene expression
Drugs			Raloxifene Afimoxifene
Diseases
GWAS			Blood protein levels ( 30072576 29875488) Pancreatic cancer ( 22158540)
Interacting Genes		1 interacting genes: TFF1	20 interacting genes: AKT1 APC ATM BTN3A1 BTNL8 CD300LD ESR2 FCRL4 FGFR2 GKN2 MUC6 RAD51 SGTB SIGLEC8 TSG101 UBQLN1 UBQLN4 VSNL1 XRCC3 ZNF250
Entrez ID		27181	7031
HPRD ID		16132	00219
Ensembl ID		ENSG00000105366	ENSG00000160182
Uniprot IDs		Q9NYZ4	P04155
PDB IDs		2N7A 2N7B	1HI7 1PS2 6V1D
Enriched GO Terms of Interacting Partners?
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