CACYBP and PEA15

Data Source:
BioGRID (two hybrid)

		CACYBP	PEA15
Description		calcyclin binding protein	proliferation and apoptosis adaptor protein 15
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GO Annotations	Cellular Component	Nucleus Nuclear Envelope Lumen Nucleoplasm Cytosol SCF Ubiquitin Ligase Complex Beta-catenin Destruction Complex Neuron Projection Cell Body Extracellular Exosome	Nucleoplasm Cytosol Microtubule Associated Complex
	Molecular Function	Protein Binding Tubulin Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity S100 Protein Binding	Protein Binding
	Biological Process	Heart Development Aging Positive Regulation Of DNA Replication Cardiac Muscle Cell Differentiation Response To Growth Hormone Negative Regulation Of Cell Death Cellular Response To Calcium Ion Cellular Response To Leukemia Inhibitory Factor	MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways			RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS
Interacting Genes		20 interacting genes: BEX3 CCR2 CD8A ERBB2 FBXO7 HSP90AA1 HSP90B1 MAPK1 NPM1 PEA15 PINX1 PRKCA S100A1 S100A12 S100A6 S100B S100P SIAH1 SIAH2 SKP1	40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13
Entrez ID		27101	8682
HPRD ID		07316	04579
Ensembl ID		ENSG00000116161	ENSG00000162734
Uniprot IDs		A0A024R904 Q9HB71	B1AKZ4 B1AKZ5 Q15121 Q96FS5
PDB IDs		1X5M 2A25 2A26	4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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