SND1 and GTF2E1

Data Source:
HPRD (in vivo, in vitro)

		SND1	GTF2E1
Description		staphylococcal nuclease and tudor domain containing 1	general transcription factor IIE subunit 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane RISC Complex Melanosome Extracellular Exosome Dense Body	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Transcription Preinitiation Complex
	Molecular Function	Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity Endoribonuclease Activity Protein Binding Cadherin Binding RISC Complex Binding	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding
	Biological Process	Osteoblast Differentiation Regulation Of Transcription, DNA-templated RNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Viral Process Gene Silencing By RNA RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Transcription Open Complex Formation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II
Pathways		Signaling by BRAF and RAF fusions	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 32499647 23532257)	Obesity-related traits ( 23251661)
Interacting Genes		23 interacting genes: APP CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 LZTR1 MAK MYB MYBL2 PIM1 POLR2A PRPF8 PTGER4 RBPJ RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I	34 interacting genes: APP CBFA2T2 CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 IKBKG NRARP PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBC1D21 TBP TCEA1 TLE5 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1
Entrez ID		27044	2960
HPRD ID		03714	01799
Ensembl ID		ENSG00000197157	ENSG00000153767
Uniprot IDs		A0A140VK49 Q7KZF4	P29083
PDB IDs		2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O	1VD4 2JTX 2RNQ 2RNR 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L
Enriched GO Terms of Interacting Partners?
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