SND1 and PRPF8

Data Source:
BioGRID (pull down)

		SND1	PRPF8
Description		staphylococcal nuclease and tudor domain containing 1	pre-mRNA processing factor 8
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Membrane RISC Complex Melanosome Extracellular Exosome Dense Body	Nucleus Nucleoplasm U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 1 Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Transcription Coregulator Activity RNA Binding Nuclease Activity Endonuclease Activity Endoribonuclease Activity Protein Binding Cadherin Binding RISC Complex Binding	RNA Binding Protein Binding Metallopeptidase Activity U6 SnRNA Binding U1 SnRNA Binding U2 SnRNA Binding U5 SnRNA Binding Isopeptidase Activity K63-linked Polyubiquitin Modification-dependent Protein Binding Pre-mRNA Intronic Binding
	Biological Process	Osteoblast Differentiation Regulation Of Transcription, DNA-templated RNA Catabolic Process Regulation Of Cell Cycle Process MiRNA Catabolic Process Viral Process Gene Silencing By RNA RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Spliceosomal Tri-snRNP Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing Proteolysis RNA Splicing Cellular Response To Lipopolysaccharide Cellular Response To Tumor Necrosis Factor
Pathways		Signaling by BRAF and RAF fusions	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases			Retinitis pigmentosa (RP)
GWAS		Birth weight ( 31043758) Brain morphology (MOSTest) ( 32665545) Cadmium levels ( 26025379) Coffee consumption ( 31046077) Estimated glomerular filtration rate ( 31152163) Fruit consumption ( 32066663) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Hemoglobin A1c levels ( 29403010) Number of sexual partners ( 30643258) Offspring birth weight ( 31043758) Subcortical volume (MOSTest) ( 32665545) Type 2 diabetes ( 32499647 23532257)	Blood protein levels ( 28240269) Calcium levels ( 20705733) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Ischemic stroke ( 29531354) Stroke ( 29531354)
Interacting Genes		23 interacting genes: APP CREBBP CSNK2A1 ESR1 GTF2E1 GTF2E2 LZTR1 MAK MYB MYBL2 PIM1 POLR2A PRPF8 PTGER4 RBPJ RNU1-1 RNU2-1 RNU4-1 RNU5A-1 RNU6-1 STAT6 SUMO2 UBE2I	21 interacting genes: ABCA1 DHX9 DUX4 ERG GPKOW H2BC5 HNRNPH2 NEDD4 PIN1 PRPF19 PTEN RNF20 SERPINB2 SLC22A2 SND1 SNRNP200 SUMO2 TP53 UBC UBE2I ZNF830
Entrez ID		27044	10594
HPRD ID		03714	06295
Ensembl ID		ENSG00000197157	ENSG00000174231
Uniprot IDs		A0A140VK49 Q7KZF4	Q6P2Q9
PDB IDs		2E6N 2HQE 2HQX 2O4X 3BDL 3OMC 3OMG 4QMG 5M9O	3E9L 3ENB 3JCR 3LRU 4JK7 4JK8 4JK9 4JKA 4JKB 4JKC 4JKD 4JKE 4JKF 4JKG 4JKH 4KIT 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6S8Q 6S9I 6ZYM 7A5P
Enriched GO Terms of Interacting Partners?
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