GTF2E1 and NRARP

Data Source:
BioGRID (two hybrid)

		GTF2E1	NRARP
Description		general transcription factor IIE subunit 1	NOTCH regulated ankyrin repeat protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Transcription Preinitiation Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding	Protein Binding
	Biological Process	Transcription Open Complex Formation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Branching Involved In Blood Vessel Morphogenesis Positive Regulation Of Endothelial Cell Proliferation Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Notch Signaling Pathway Somite Rostral/caudal Axis Specification Negative Regulation Of T Cell Differentiation Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Notch Signaling Pathway Involved In Somitogenesis
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Macular thickness ( 30535121)
Interacting Genes		34 interacting genes: APP CBFA2T2 CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 IKBKG NRARP PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBC1D21 TBP TCEA1 TLE5 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1	2 interacting genes: GTF2E1 IKBKG
Entrez ID		2960	441478
HPRD ID		01799	17564
Ensembl ID		ENSG00000153767	ENSG00000198435
Uniprot IDs		P29083	Q7Z6K4
PDB IDs		1VD4 2JTX 2RNQ 2RNR 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L	6PY8
Enriched GO Terms of Interacting Partners?
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