UTP25 and RUFY1

Data Source:
BioGRID (two hybrid, two hybrid, two hybrid)

		UTP25	RUFY1
Description		UTP25 small subunit processor component	RUN and FYVE domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Small-subunit Processome	Cytoplasm Endosome Cytosol Nuclear Speck Early Endosome Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	RNA Binding Protein Binding RRNA Binding U3 SnoRNA Binding	Protein Binding Lipid Binding SH3 Domain Binding SH2 Domain Binding Metal Ion Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Multicellular Organism Development Protein Catabolic Process Protein Destabilization Positive Regulation Of Embryonic Development	Phosphatidylinositol Biosynthetic Process Endocytosis Small GTPase Mediated Signal Transduction Protein Transport Regulation Of Endocytosis
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol	Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Daytime sleep phenotypes ( 27126917) Dental caries (decayed and filled deciduous teeth) ( 31533690) Eating disorders ( 22911880) Lung cancer ( 28604730) Monocyte percentage of white cells ( 32888494) TPE interval (resting) ( 32386560)
Interacting Genes		11 interacting genes: AP2M1 APP CEP70 MAGEA11 MEOX2 MID2 MIPOL1 RUFY1 TRIM62 TRIM9 ZBTB10	18 interacting genes: AP3B2 AP3D1 AP3M1 AP3S1 BMX EPHA3 GIT2 ITSN2 OAS1 PIAS2 RAB14 RAB39B RAB3IP RAB4A RAB5A TRIM23 TXNDC17 UTP25
Entrez ID		27042	80230
HPRD ID		14535	15282
Ensembl ID		ENSG00000117597	ENSG00000176783
Uniprot IDs		Q68CQ4	A8K7B1 Q96T51
PDB IDs			2YQM 2YW8
Enriched GO Terms of Interacting Partners?
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