UTP25 and ZBTB10

Data Source:
BioGRID (two hybrid)

		UTP25	ZBTB10
Description		UTP25 small subunit processor component	zinc finger and BTB domain containing 10
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Small-subunit Processome	Nucleus Nucleoplasm
	Molecular Function	RNA Binding Protein Binding RRNA Binding U3 SnoRNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) RRNA Processing Multicellular Organism Development Protein Catabolic Process Protein Destabilization Positive Regulation Of Embryonic Development	Regulation Of Transcription By RNA Polymerase II
Pathways		rRNA modification in the nucleus and cytosol Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Asthma ( 31361310 31959851 30929738 27182965 32296059 29273806) Asthma (adult onset) ( 31036433 30929738) Asthma (childhood onset) ( 31036433 30929738) Asthma and hay fever ( 24388013) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 22197932 26482879) Basal cell carcinoma ( 27539887) Body mass index ( 28892062 30271922 25673413) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549) Hematocrit ( 32888494) Hypothyroidism ( 22493691) Late-onset myasthenia gravis ( 26562150) Mean platelet volume ( 32888494) Platelet distribution width ( 32888494) Self-reported allergy ( 23817569) Self-reported risk-taking behaviour ( 30271922) Sex hormone-binding globulin levels ( 22829776) Urinary albumin-to-creatinine ratio ( 31511532)
Interacting Genes		11 interacting genes: AP2M1 APP CEP70 MAGEA11 MEOX2 MID2 MIPOL1 RUFY1 TRIM62 TRIM9 ZBTB10	20 interacting genes: CDC7 CEP19 DCX DDX6 EHHADH FUT8 HRAS LSM4 MAGOHB MOB3C MORF4L1 MORF4L2 MYO15B PACRGL PHF1 RBM41 RNF8 USP20 UTP25 ZNF417
Entrez ID		27042	65986
HPRD ID		14535	15689
Ensembl ID		ENSG00000117597	ENSG00000205189
Uniprot IDs		Q68CQ4	Q96DT7 Q9H9H3
PDB IDs
Enriched GO Terms of Interacting Partners?
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