IL36RN and SSBP2

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		IL36RN	SSBP2
Description		interleukin 36 receptor antagonist	single stranded DNA binding protein 2
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Cytokine Activity Interleukin-1 Receptor Binding Interleukin-1 Receptor Antagonist Activity Protein Binding	Single-stranded DNA Binding
	Biological Process	Negative Regulation Of Cytokine-mediated Signaling Pathway Inflammatory Response To Antigenic Stimulus Inflammatory Response Cytokine-mediated Signaling Pathway Antifungal Humoral Response Negative Regulation Of Interferon-gamma Production Negative Regulation Of Interleukin-17 Production Negative Regulation Of Interleukin-6 Production Innate Immune Response Cellular Response To Lipopolysaccharide	Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Interleukin-36 pathway
Drugs
Diseases
GWAS		Menstruation quality of life impact (dysmenorrhea) ( 29855537) Pain medicine use during menstruation ( 29855537) Stroke ( 26089329)	Adult body size ( 32376654) Anorexia nervosa ( 21079607) Bipolar disorder ( 31043756) Glioblastoma ( 22472174) Plateletcrit ( 32888494)
Interacting Genes		18 interacting genes: AGR2 AP3M1 CNOT4 CRACR2B DDIT4L HPCA INCA1 IRAK4 MCM6 REL SH2B2 SKIL SSBP2 SSBP3 SSBP4 UBL4B ZKSCAN4 ZNF512B	7 interacting genes: CDK6 EWSR1 IL36RN LDB1 LDB2 PIN1 TOM1
Entrez ID		26525	23635
HPRD ID		16112	09577
Ensembl ID		ENSG00000136695	ENSG00000145687
Uniprot IDs		A0A024R518 Q9UBH0	A0A087X159 P81877
PDB IDs		4P0J 4P0K 4P0L	6IWV 6TYD
Enriched GO Terms of Interacting Partners?
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