CHORDC1 and TCAP

Data Source:
BioGRID (two hybrid)

		CHORDC1	TCAP
Description		cysteine and histidine rich domain containing 1	titin-cap
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GO Annotations	Cellular Component	Cellular_component	Cytosol Z Disc I Band
	Molecular Function	Protein Binding ATP Binding Zinc Ion Binding ADP Binding Hsp90 Protein Binding	Protein Binding Structural Constituent Of Muscle Protein-macromolecule Adaptor Activity Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding
	Biological Process	Regulation Of Centrosome Duplication Centrosome Duplication Chaperone-mediated Protein Folding Regulation Of Cellular Response To Heat Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Protein-containing Complex Assembly
Pathways			Striated Muscle Contraction
Drugs
Diseases			Limb-girdle muscular dystrophy (LGMD)
GWAS		Basophil count ( 32888494) Basophil percentage of white cells ( 27863252) White blood cell count (basophil) ( 27863252)	Alcohol consumption ( 31358974) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Ulcerative colitis ( 20228799)
Interacting Genes		7 interacting genes: HSP90AA1 HSP90AB1 NAP1L1 PAK1 PPP5C TCAP XPO1	38 interacting genes: ADPGK ANKRD2 ASB6 ATXN1 BLZF1 C19orf54 CDCA4 CHORDC1 CRK ENO1 ENO3 FAM153B FAS FYN HSPA8 HSPB2 HSPB3 HSPG2 IKZF3 KLHL41 KRTAP19-7 LAMTOR5 LHX4 MDM2 MSTN MYOZ1 MYOZ3 NUP133 PAX7 PDPK1 RELA SAPCD1 SIVA1 TRIM54 TRIM55 TRIM63 TTC19 TTN
Entrez ID		26973	8557
HPRD ID		05072	05133
Ensembl ID		ENSG00000110172	ENSG00000173991
Uniprot IDs		Q9UHD1	A2TDC0 O15273
PDB IDs		2YRT	1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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