TCAP and ADPGK

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		TCAP	ADPGK
Description		titin-cap	ADP dependent glucokinase
Image			No pdb structure
GO Annotations	Cellular Component	Cytosol Z Disc I Band	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Protein Binding Structural Constituent Of Muscle Protein-macromolecule Adaptor Activity Titin Binding BMP Binding Ion Channel Binding FATZ Binding Titin Z Domain Binding	ADP-specific Glucokinase Activity Metal Ion Binding
	Biological Process	Somitogenesis Skeletal Muscle Contraction Cardiac Muscle Hypertrophy Adult Heart Development Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Otic Vesicle Formation Response To Muscle Stretch Detection Of Muscle Stretch Sarcomere Organization Cardiac Muscle Fiber Development Sarcomerogenesis Detection Of Mechanical Stimulus Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Protein-containing Complex Assembly	Glucose Metabolic Process Canonical Glycolysis
Pathways		Striated Muscle Contraction	Glycolysis
Drugs
Diseases		Limb-girdle muscular dystrophy (LGMD)
GWAS		Alcohol consumption ( 31358974) Asthma ( 31959851 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Pancreatic ductal adenocarcinoma ( 30541042) Refractive error ( 32231278) Ulcerative colitis ( 20228799)	Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Hand grip strength ( 29691431) Triglyceride levels ( 28334899) Urate levels ( 23263486) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		38 interacting genes: ADPGK ANKRD2 ASB6 ATXN1 BLZF1 C19orf54 CDCA4 CHORDC1 CRK ENO1 ENO3 FAM153B FAS FYN HSPA8 HSPB2 HSPB3 HSPG2 IKZF3 KLHL41 KRTAP19-7 LAMTOR5 LHX4 MDM2 MSTN MYOZ1 MYOZ3 NUP133 PAX7 PDPK1 RELA SAPCD1 SIVA1 TRIM54 TRIM55 TRIM63 TTC19 TTN	4 interacting genes: GDF9 TADA3 TCAP UBQLN4
Entrez ID		8557	83440
HPRD ID		05133	12429
Ensembl ID		ENSG00000173991	ENSG00000159322
Uniprot IDs		A2TDC0 O15273	Q9BRR6
PDB IDs		1YA5 2F8V
Enriched GO Terms of Interacting Partners?
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