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GEM and AHCYL1
Data Source:
BioGRID
(two hybrid, two hybrid)
GEM
AHCYL1
Description
GTP binding protein overexpressed in skeletal muscle
adenosylhomocysteinase like 1
Image
GO Annotations
Cellular Component
Nucleus
Plasma Membrane
Cytoplasmic Side Of Plasma Membrane
Midbody
Spindle Midzone
Mitotic Spindle
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Apical Plasma Membrane
Mitochondria-associated Endoplasmic Reticulum Membrane
Extracellular Exosome
Molecular Function
Magnesium Ion Binding
GTPase Activity
Calcium Channel Regulator Activity
Protein Binding
Calmodulin Binding
GTP Binding
GDP Binding
RNA Binding
Adenosylhomocysteinase Activity
Protein Binding
Identical Protein Binding
Biological Process
Mitotic Cell Cycle
Immune Response
Signal Transduction
Cell Surface Receptor Signaling Pathway
Chromosome Organization
Metaphase Plate Congression
Negative Regulation Of High Voltage-gated Calcium Channel Activity
MRNA Polyadenylation
Protein Export From Nucleus
One-carbon Metabolic Process
Apoptotic Process
Positive Regulation Of Sodium Ion Transport
Regulation Of MRNA 3'-end Processing
Regulation Of Ion Transmembrane Transporter Activity
S-adenosylmethionine Cycle
Angiotensin-activated Signaling Pathway
Epithelial Fluid Transport
Regulation Of Anion Transport
Response To Calcium Ion
Regulation Of Cardiac Conduction
Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways
PLC beta mediated events
DAG and IP3 signaling
Role of phospholipids in phagocytosis
FCERI mediated Ca+2 mobilization
Regulation of insulin secretion
VEGFR2 mediated cell proliferation
Ion homeostasis
Ion homeostasis
CLEC7A (Dectin-1) induces NFAT activation
FCGR3A-mediated IL10 synthesis
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
Carotid plaque burden (
28282560
)
Coronary artery disease (
29212778
33020668
)
Pulse pressure (
30578418
)
Height (
31562340
)
Interacting Genes
128 interacting genes:
A2M
AHCYL1
ANKRD36B
APOH
ASB15
BEGAIN
BHLHB9
BLOC1S2
BLZF1
BMP1
C1orf131
CACNB3
CALM1
CARD9
CCDC102B
CCDC125
CCDC88B
CDR2
CEP70
CLDN15
CLEC4G
COG6
COG8
CTSL
CYSRT1
DBF4B
DEUP1
DISC1
ECSIT
EFHC2
EXOSC8
GADD45GIP1
GAS8
GMIP
GOLGA2
GOLGA6L9
GOPC
HOOK2
HSF2BP
IHO1
IKZF3
INCA1
INO80E
INSC
ISCA2
KATNBL1
KCTD9
KIFC3
KLC3
KRT31
KRT34
KRT36
KRT40
KRT6A
KRT83
KRTAP10-3
KRTAP10-7
KRTAP10-8
LIMS1
LRP2BP
LZTS2
MCRS1
MESD
MGLL
MID2
MIPOL1
MKRN3
MORN3
MSS51
MTUS2
MYOG
NDUFAF3
NDUFB7
NDUFS8
NOTCH2NLA
OIP5
PBX4
PDLIM7
PIH1D1
PLAGL2
PLEKHF2
PNMA1
POF1B
PRDM14
PRDM6
RNF7
RUNDC3A
SDHB
SNAP91
SORBS3
SPAG5
SPATA6
SSX2IP
TBC1D3B
TBC1D3G
TCF4
TFIP11
TGM7
TLE5
TP53BP2
TRAF1
TRAF2
TRIM10
TRIM23
TRIM27
TRIM32
TRIM54
TRIM69
USH1G
USHBP1
VIM
VPS28
VPS52
VTN
WWOX
YBEY
YPEL3
YWHAB
ZBTB42
ZC4H2
ZMAT5
ZNF20
ZNF552
ZNF655
ZNF688
ZNF774
ZRANB1
ZSCAN9
25 interacting genes:
BID
CDKN2C
DACH1
GEM
HBQ1
HEXIM2
HGS
HSPA6
ITPR1
JOSD2
LRRK2
MEOX2
MFHAS1
PLEKHG5
PPL
PRDM6
PSMD9
RNF6
SLC23A1
SOX30
SRPK1
SRPK2
SUMO2
UACA
ZNF165
Entrez ID
2669
10768
HPRD ID
11553
07613
Ensembl ID
ENSG00000164949
ENSG00000168710
Uniprot IDs
A0A024R9F5
P55040
A0A024R0A8
O43865
PDB IDs
2CJW
2G3Y
2HT6
3MTG
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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