GDI1 and RAB3B

Data Source:
BioGRID (pull down)

		GDI1	RAB3B
Description		GDP dissociation inhibitor 1	RAB3B, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Axon Midbody Protein-containing Complex Neuronal Cell Body Myelin Sheath	Cytoplasm Endosome Golgi Apparatus Cytosol Plasma Membrane Synaptic Vesicle Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Dopaminergic Synapse Anchored Component Of Synaptic Vesicle Membrane
	Molecular Function	GDP-dissociation Inhibitor Activity Rab GDP-dissociation Inhibitor Activity GTPase Activator Activity Protein Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Signal Transduction Protein Transport Vesicle-mediated Transport Rab Protein Signal Transduction Positive Regulation Of GTPase Activity Positive Regulation Of Axon Extension Negative Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Response To Calcium Ion Negative Regulation Of Protein Targeting To Membrane	Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Antigen Processing And Presentation Positive Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Localization To Plasma Membrane Regulation Of Vesicle Size Regulation Of Synaptic Vesicle Cycle
Pathways		RAB GEFs exchange GTP for GDP on RABs	RAB geranylgeranylation
Drugs
Diseases		Non-syndromic X-linked mental retardation
GWAS			Mean platelet volume ( 32888494)
Interacting Genes		15 interacting genes: CDC42 EPB41 GNL1 LNX1 PSEN1 RAB1B RAB27A RAB3B RAB6A RAB9A RABAC1 RAC2 RHOH TK1 UBQLN4	16 interacting genes: ACVR1 CALM1 CALM2 CALM3 CHM GDI1 PIGR RABIF RIMS2 RPH3A RPH3AL SGSM2 SMAD1 SMAD4 TGFBR1 VRTN
Entrez ID		2664	5865
HPRD ID		02114	01540
Ensembl ID		ENSG00000203879	ENSG00000169213
Uniprot IDs		A0A0S2Z3X8 P31150	P20337
PDB IDs			3DZ8
Enriched GO Terms of Interacting Partners?
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